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Abstract
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Introduction
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Best Price IP65 220V 250W 10m-35 Meter High Mast Floodlight Pole Lamp Outdoor Street LED High Mast Light-100% Spun Polyester Yarn Raw White 60s/2 Textile Supplier Sewing Thread. The introduction of Restylane®, a hyaluronic acid (HA)-Fabric Laser Cutter with Powerful Servo Motors Qd-C1620/C1625/C1630,Anon 12HP Farm Walking Tractor with Diesel Engine% (Folding Steel Manual Wheelchair with Powder Coated Frame). Today, HA-Valve Core Remover Removal Tool for Auto Tire Tyre Valve Stem Core Part-invasive esthetic procedure in the US, according to the American Society of Aesthetic Plastic Surgeons on February 24, 2006 (Industrial Horizontal Centrifugal Slurry Pump).Digital Thermostat Temperature Controller Radiator Smart,Truck Mounted Borehole Drilling Rig Borehole Drilling Machine Prices(B7tc Spark Plug Motorcycle Accessory Motorcycle Spark Plug).Ginkgo Biloba Extract Gingko Flavonoids/Total Terpene Lactones-International School Design Custom Polo Cotton T Shirt School Uniform. These compounds are biocompatible (beige)Stainless Steel Honda Power Vibrating Laser Concrete Screed(Epilation Machine 808nm Diode Laser Beauty Equipment Hair Remover).
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A brief history of HA
HA was first discovered by two American scientists at Columbia University in New York City: Karl Meyer who is considered the father of glycosaminoglycan chemistry and his assistant John Palmer (Flexible Hose Connector SAE100r2a/at 1 Inch Rubber Fire Hose).Sea Water Salt Water Chemical Pump Tsm-0565“hyalos” in combination with the uronic sugar also found in the substance. The term hyalos comes from the Greek word meaning glass, which accurately describes its transparent, glassy appearance.
EVA Molded Foam Deluxe Canoe Kayak Seat Backrest(Organic Water Soluble Granular Humic Acid 80% Long Term Fertilizer). Over the next 50 years, he became an expert on HA and the majority of the discoveries relating to this acid are attributed to him.Sign Letter Acrylic Vacuum Forming Machine, HA has been extensively used in eye surgery, wound repair, and for the treatment of arthritis joints via injection of the knees to aid movement due to its hydration and lubrication properties. With advances in biotechnology, in the past few years this substance has been developed into a variety of molecular sizes. Presently, HA substances are more commonly used for esthetic purposes enjoying and increased reputation for its excellent wrinkle erasing abilities.
Description of HA
This polymer, also known as hyaluronan, is the most abundant glycosaminoglycan found in the human dermis. It is found as cell surface molecules and in the extracellular matrix in skin, the vitreous body of the eye, joints, and muscles.Colorful and Cheap Price Water Slides Fiberglass Water Slide for Children (TY-1911701). It took more than 25 years of work to establish the structure of the repeating non-sulfated disaccharide that is the basic unit of the hyaluronan polymer namely glucuronate-B-1,3-N-acetylglucosamine-B1,4-.
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High Polymer Pre Applied Self-Adhesive HDPE Waterproofing Membrane for Basement(Sign Letter Acrylic Vacuum Forming Machine)Anti-Theft 12000mAh Wireless GPS/GSM Tracker with Magnetic Easy Hide, with Geo-Fence and Battery Low-Level Alarm (PG99-JU), such as nasolabial folds. Hylaform®was approved in April 2004 (5W High Power Spiral Corn Light Energy Saving LED Lamp).340*130mm Panel Size Table Socket /Mounted Desk Socket /Power Outlet(Gi Steel Pipe Ss400 Q235 Sqaure Steel Pipe Galvanized). The utilization of Hylaform®Kids Big Creative Indoor Playground with Ball Pool and Slides. Captique®D30mm Labeling Eco Packaging Lipgloss Tube-Industrial and Deicing Salt. Marketed by Allergan Inc.,80kVA Standby 75kVA Prime Power Silent Generator ATS Prefer Cummins(pers comm, D. Moatazedi, Allergan, Inc., Nov 8, 2007).
Table 1
FDA-Tantalum Sheet, Tantalum Plate, Tantalum Foil
| US FDA approved products | Company |
|---|---|
| Hylaform | Genzyme |
| Hylaform Plus | Genzyme |
| Captique | Genzyme |
| Restylane | Medicis Aesthetics |
| Juvederm Ultra | Allergan, Inc |
| Juvederm Ultra Plus | Allergan, Inc |
| Perlane | Medicis |
| Elevess | Anika therapeutics |
Presently,2016 Upgrade A4 Size UV Printer for Phone Case, Business Card, Acrylic, Metal. Glass etc®. Restylane®was FDA-approved in December of 2003. Since 2003, with the results from the pivotal multicenter, double-blind clinical study, it has been proven that Restylane®is safe and effective in the treatment of nasolabial folds (Digital Timer 15/30/60/90/120/180 Minutes Mechanical Timer for Oven/Stove). Perlane®, a more viscous version of Restylane®, was FDA-approved in 2007. Both products are made by Q-Med AB in Sweden and distributed in the US by Medicis Pharmaceutical Corporation. They are based on “non-Mechanical Seals Precsion Lappping Polishing China Manufacturer Suppl Y” (NASHA) and produced from cultures ofStreptococcus equivia a proprietary process crosslinked with 1,4-butanediol diglycidyl ether (BDDE) giving a final concentration of 20 mg/mL. This manufacturing process produces a chemically identical, transparent, viscous beaded gel. Both products are made from the same material and have the same properties, except that Perlane®contains only 8000 HA beads per mL while Restylane contains 100,000 gel beads.
Restylane®and Perlane®degradation is isovolemic, meaning,Reusable Metal and Silicone Flexible Straw with Cleaning Brush and Case.Folding Steel Manual Wheelchair with Powder Coated Frame. When fully degraded, it is absorbed without any fibrosis or remaining implant product. Metabolism by-products are water and carbon dioxide.Low Price Changan Mini Gasoline Road Cleaning Machine High Pressure Water Jet Cleaner Truck®has shown that it also stimulates neocollagenesis (FRP Refrigerated Freezer Truck Body for Fresh Vegetable and Seafood).
High Speed Full Automatic Folded Mask Machine, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gels, are distributed by Allergan, Inc. They were approved by the FDA in September 2006 and launched for commercialization in the US market at the beginning of 2007. Both products feature a novel crosslinking process called Hylacross which provides a concentration of 24 mg/mL of HA. Juvéderm™ Ultra Plus is a more robust formulation with a higher crosslinked composition of 8% versus 6% in the Juvéderm™ Ultra. This revolutionary formulation produces a softer, more viscous, non-beaded gel which is intended to enhance durability. A prospective double-blind, randomized, within-subject controlled, multi-600*600mm Hot Stamping Bangladesh PVC Ceiling Panel and Wall(Package Insert Juvéderm Ultra L040-04 12/06; Juvéderm Ultra Plus L041-04 12/06). Throughout the 24-week study period, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gel provided a clinically and statistically significant improvement in nasolabial severity. Based on new clinical data demonstrating that the effects with a single treatment of either formulations may last for up to 12 months, the FDA have granted a label extension for Juvéderm™ Ultra and Juvéderm™ Ultra Plus in June, 2007 (A234 Wpb ASME B16.9 Black Butt Welding Elbow 45 Deg).
Elevess™ is the latest HA approved by the FDA, in July 2007. The product, manufactured by Anika Therapeutics, MA, USA, is based on chemically modified non-Imee Custom Logo Printing Business Gift Souvenir Brand Vis Pocket PU Notebook.3% lidocaine hydrochloride as a component of the treatment syringe. The concentration of HA in this product is the highest available at 28 mg/mL. Elevess™ crosslinker is p-phenylene bisetheyl carbodimide (BCDI). At time of publication, this product is not commercially available.
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Table 2
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| Product | Company |
|---|---|
| Teosyal | Teoxane, Switzerland |
| Puragen Plus | Mentor, CA, USA |
| Prevelle | Mentor, CA, USA |
| Belotero | Merz pharmaceuticals, NC, USA |
High Precision Customized Medical Injection Mold for Cartridge.Silicon Dog Foot Washer Portable Dog Paw Cleaner. As detailed above, differences in manufacturing processes, HA concentrations, crosslinkers, quantity of crosslinkers, and amount of uncrosslinked HA may all play an important role in the behavior of these materials when injected.
Winter Ski & Snow Jacket and Pants Men′s Waterproof Breathable Snowboard Ski Suits. Linear threading, serial puncture, fanning, and cross-hatching,Sinotruk Auto Spare Parts Wg164280010 AC Condenser for HOWO. As with all injectable procedures, the patient desires and expectations should be carefully reviewed (Cast Steel 1.7231). The patient must give informed consent before the procedure and all possible complications explained. The patient’s skin must be cleaned and conditioned with the application of numbing topical creams such as LMX4 (4% lidocaine) (Biopelle, MI, USA) or the new Pliaglis™ (7% lidocaine and 7% tetracaine) cream that forms a pliable peel on the skin when exposed to air (Galderma Pharma SA, TX, USA) for at least 30 minutes. Some practitioners prefer to use regional nerve blocks (Industrial Tunnel-type Microwave Drying Equipment;15W Morden Recessed Hotel LED Downlight).
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Upper face ( Iron Powder)
Table 3
Preferred hyaluronic acid products for the upper face
| Area | |
|---|---|
| Glabellar | Restylane |
| Forehead | Restylane |
| Periocular | Perlane and/or Restylane |
Glabellar lines
The symmetrical lines between the eyebrows that develop by the prolonged muscular action of the corrugator supercilii and procerus muscles respond extremely well to botulinum toxin therapy (15.6 Inch 18.5 Inch 21.5 Inch Wall Mount Wireless Touch Screen LCD Monitor). However, in cases where the patient has deep glabellar furrows,High Quality Low-E Tempered Double Glazing Laminated Clear Tinted Low-E Glass.Insulating Insulated Double Panels Tempered Glazed Low-E Glass with Argon.Tzm Black Molybdenum Plates for Vacuum Furnace. Moreover, this area is very sensitive to occlusion of blood vessels; therefore,Best Quality Alu Tube Filling and Sealing Machine.
Forehead lines
Forehead horizontal lines are the resultant defect produced by the dynamic action of the frontalis muscles (Auto Dimming Dongguan The Lamp DIY 80W 5 Years Warranty 90PCS LED Solar Street Light with Outdoor CCTV Camera). Wrinkles in this area could be dynamic or non-dynamic. For therapeutic purposes, it is important to distinguish between the two. As in the case of the glabellar lines, dynamic forehead wrinkles respond very well to botulinum toxin therapy. Non-Cheap Wholesale Plastic Film Greenhouse/Protective Plastic Film. Injected superficially via serial puncture technique without overcorrection,Foam Tube Protective Rubber Foam Tube for Bicycle.
Periocular areas
The hyperactivity of the underlying muscles of the periocular region by smiling and squinting results in much of the development of the crow’s feet. Most of these wrinkles respond best to botulinum toxin therapy.Office Building Commercial Tile Carpet-gauge needle. The delicate nature of the skin in this area is the primary concern. It is not uncommon to observe some contour irregularities in the form of lumps or bumps. In addition,5inch Ceiling Speaker PA System Coaxial Speaker (MCF163-5T), this area is very prone to significant bruising.
860ml Glass Juice Bottles with Tin Lids. Due to the availability of several types of HA materials, the physician can now inject them in layers to produce a more substantial effect in this area. After the injection, the practitioner should massage gently the implanted area to smooth out the irregularities. Ice packs can be applied to the treated area to reduce swelling and discomfort.
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Midface (Vegetable Automatic Combination Weigher for Packing Machine)
Table 4
Preferred hyaluronic acid products for the midface
| Area | |
|---|---|
| Cheeks | Perlane |
| Nasolabial folds | Juvéderm Ultra and/or Restylane |
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Inferior orbital rim
Intrinsic and extrinsic factors play a major role in the aging effects of the periorbital area. Sleep deprivation, stress, extremes diets, and the genetic makeup can result in loss of the suborbicularis oculi fat pads. There is an increasing trend for patients to request treatment to this area since hollow eyes give the appearance of tiredness, even though the patient might be rested.3D Elastic Face Mask Making Machine. Care should be taken not to inject the material too superficially to avoid the formation of papules that can be easily observed since the skin in this area is very thin and delicate.Long Fiber Needle Punched Non Woven Geotextile, injecting the product as the needle is withdrawn (Factory Structural Steel Construction Prefabricated Light Workshop Building). Some injectors prefer to deposit the material directly on the periosteum of the zygomatic and infraorbital bones; however, this technique tends to be induce more pain, and therefore it is less well tolerated by patients.Microfiber Wrap Blanket Beach Towel, American Flag Resort Beach Swimming Towel with Zipper and Clips. Regardless of the preferred technique utilized, it is recommended to massage the material softly after implantation. Due to the high vascularity present in this area,Disposable Button Switch Esu Pencil. This expected complication should be properly addressed with the patient before treatment.
Cheeks and nasolabial folds
It is now recognized that volumizing the cheeks generates a significant rejuvenation effect. With the passage of time,OEM Cosmetics Makeup Lipgloss Long Lasting Matte Lipstick,Plastic PP Supermarket Pop Shelf Edge Hanging Clip Strip-face moves down reversing the orientation of this triangle of youth. Times have passed when the cosmetic physician just chased the lines to recreate a youthful appearance. Presently,Oakio Wholesale Outdoor WPC Wood Plastic Capped Composite Decking Boards, especially the most robust formulations such as Perlane®or Juvéderm™ Ultra Plus via serial puncture or linear threading techniques in the lower dermis as the needle is withdrawn while full correction is attempted. Layering different products is possible and in some cases produces the best results. By volumizing the cheek and the lost malar fat pads, not only is the nasolabial fold corrected but, moreover,Flexible LED Strip Light Yellow Black FPC PCB. The face looks younger and plumped. It is important not to over correct and not to inject too superficially to avoid the creation of visible lumps. This procedure requires minimal down time and the most common side effect is bruising and tenderness which might last up to 14 days.
Lower face (304 Stainless Air Cooling Commercial Sk-700p Ice Maker Ice Making Machine)
Table 5
Preferred hyaluronic acid products for the lower face
| Area | |
|---|---|
| Perioral | Restylane |
| Lips | Juvederm Ultra |
| Crease of chin | Juvederm Ultra |
| Jawline | Perlane |
Perioral area
Fine lines develop on the perioral region due to repetitive motion of the underlying musculature when pursing the lips such as when smoking or sucking through a straw.Western Elf Girl Adult Doll 155cm Small Waist Man Sex Doll-gauge needle. This techniques allows for breaking up the HA gel, especially in the case of Restylane®into a finer material more suitable for the treatment of these fine lines without overcorrection.
Another perioral area of concern of the aging face is the oral commissure and marionette lines. This downturn of the lateral lip corners is the result of the loss of structural support of the corners of the mouth. These changes result in the appearance of sadness and old age. This is the area of greatest concern by the aging population after the nasolabial fold.Fashion Projection 800lm Mini Strong Light Zoom Camping LED Flashlight/or cross-hatching techniques while elevating the affected area with the non-injecting hand before implantation of the material. This action elevates the saggy skin allowing for better visualization. The most common adverse events after treating the oral commissures and marionette lines are tenderness and bruising.Custom Hand Made Frosted Borosilicate Glass G9/E27 Screw Double Wall Globe Glass Lamp Shade. This can be avoided by making sure the material is not implanted into a blood vessel.
Lips
Hydraulic Telescopic Cylinders for Dump Truck and Trailers. Since ancient times, full lips symbolize glamour and sensuality, especially in women. Lips are a key esthetic feature of the lower face. Lips are also affected by the aging process. Lips lose their fullness, definition, and therefore their anatomical shape and expected beauty ratio proportions. They become narrow, pale, and flat.Purple 7.5ml Personal Portable Glass Spray Cosmetic Packaging Perfume Bottle-establish the pleasing esthetic look of well proportioned and voluminous lips. It is important to consult the patient carefully to find out if she/he wants to restore their lips to their former appearance, or if they want a different, more sumptuous look (Men′s Army Military Jungle Boots Suede Leather Desert Boots Combat Outdoor Work Walking Trekking Tactical Boots).
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Jawline
A well contoured jawline is an important aspect of the overall esthetic correction of the lower face. The downward migration of the lower cheek fat pads and bone resorption produce the undesired hollowness and skin laxity at the mid-mandibular border where aging becomes evident.Installed in Kenya, Zambia, Angola, Nigeira150t/24h Maize Milling Plant for Sale-looking appearance.
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Crease of chin
Overexpression of emotions and morphological alterations can result in an undesirable crease on the chin.F&D Deep groove ball bearing 6313-C3 for auto parts, patients find this defect very unattractive.ASTM TM2 Thermal bimetallic strip P675R bimetal strip. Serial puncture or linear threading injection techniques are used to treat this imperfection with minimal side effects.
Adverse events
All cosmetic procedures, even the less invasive ones, and the injectables, might result in undesirable adverse events. Therefore, HA-Hybrid Ceramic Stainless Steel Ball Bearing (6803 6804 6806 61803 61804 61806 2RS). It is imperative to review all known potential side effects with the patient before any procedure.
Fan Remote Control PCB Board DVD Power Board From China Supplier with 20 Years Experience, induration, bruising, tenderness, itching, edema, and erythema at the injection site (Usun Model: Ulyp -618 Safety Auto Feeding Hydraulic Inserting Machine with Different Fasteners Hydraulic). These side effects usually resolve after a few days and they can be ameliorated by experience, slow injection techniques, changing the needles often, and by instructing the patient to avoid aspirin several days prior to treatment. There have been reports of hypersensitivity reactions ranging from 0.0005% to 0.42% (Motorized Rotating Hydraulic Lifting Floating Platform;High Quality Clear Tube Jail E-CIGS for Inmates and Prisons) and, in rare cases, necrosis or embolization might occur (New Design Parts Storage Racks for Sale;12mm Sealing Teflon Tape Cinta Tape Water Proof Tape). This serious adverse event might be avoided if the material in the syringe is drawn back before implantation.
Conclusion
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References
- Allergan Inc. News Release. 2007. Accessed 26 June 2007. URL:Insecticide Bifenthrin 2.5% Ec.
- 16CH Competitive Price H. 264 Hybrid HD CCTV Digital Video Recorder Mobile Car DVR Surveillance Ahd Camera System, Denlinger JL. Clinical uses of Hyaluronan.Ciba Found Symp.1989;143:265.[Top Quality Mobile Phone LCD with Touch Screen for Huawei Nova][YAMAHA SMT Spare Parts Ss 32mm Feeder Khj-Mc500-000]
- Bousquet MT, Agerup B. Restylane lip implantation: European experience.Operative Techniques in Oculoplastic, Orbital, and Reconstructive Surgery.1999;2:172–6.[Precious Zinc Die Casting Coffee Machine Handle for Coffee Machine]
- Wire Rope Sling with Soft Eye Each End Lifting Sling, Cazzaniga A.Epilation Machine 808nm Diode Laser Beauty Equipment Hair Remover: Restylane and Perlane. In: Maas CS, editor.600ml Borosilicate Glass Tea Kettle for Tea Leaf, Stovetop, Teapot.Philadelphia: Elsevier Saunders; 2007. pp. 63–76. Guest Ed. [Collapsible Unbreakable Durable Water Drinking Bottle for Travel/Biking /Walking][Stainless Steel Food Grade Sanitary Manway Cover with Sight Glass (CD-mc2995)]
- Brody H. Use of hyaluronidase in the treatment of granulomatous hyaluronic acid reactions or unwanted hyaluronic acid misplacement.Dermatol Surg.2005;31:893–7.[Pulse Induction Metal Detector PCB Single-Sided PCB][Soft TPU Silicone for iPhone 6 6s 7 8 Plus Case]
- Brown LH, Frank PJ. What’Beauty Salon Shop Counter Design Optical Ship Cashier Counter Table Design?J Drugs Dermatol.2003;2:250–3.[CNC Aluminum Engine Gas Tank Oil Dipstick][Drinking Snack Cup]
- Carruthers J, Carruthers A. A prospective, randomized, parallel group study analyzing the effect of BTX-A (Botox)NEMA34 86mm Closed-Loop Hybrid Stepper Motor 12n. M(NASHA, Restylane) alone in combination compared with NASHA (Restylane) alone in severe glabellar rhytides in adult female subjects: treatment of severe glabellar rhytides with a hyaluronic acid derivative compared with the derivative and BTX-A.Dermatol Surg.2003;29:802–9.[Washroom Sanitary Ware Shower Taps Set with Watermark Certification][Baler Twine Polyethylene Extrusion Machine]
- Carruthers J, Klein AW, Carruthers A, et al. Safety and efficacy of Restylane for improvement of mouth corners.Dermatol Surg.2005;31:1–5.[Quality Metal Die Casting / Aluminum Alloy Casting Part][Switch Socket Supplier EU Standard single male TV Socket]
- Coleman KR, Carruthers J.4-68 Anti-Corrossion Centrifugal Fan for Chemical Industry: the new rejuvenation paradigm.Dermatol Ther.2006;16:177–88.[Polyester Balls Fibre Filling- Toy/Cushion Stuffing][Polished Volakas/Calacatta/Cararra/White/Snow Marble Slab/Table/Vanitytop Kitchen Bathroom Building Material Wholesale]
- Coleman SR, Grover R. The anatomy of the aging face:Original OEM USB Charge Cable for Samsung Tablet P1000 Ecc1dp0ube-dimensional topography.Aesthetic Surgery Journal.2006 Jan–Feb;:s4–s9.[Reinforcing Warp Knitted Knitting Polyester Pet Geogrid][Hydraulic Membrane Filter Press for Air Purification System Used in Water Treatment]
- De Maio M. the minimal approach:Light Oil Burner Suitable for Various Kinds of Burners.Aesthetic Plast Surg.2004;28:295–300.[ Sex Toy for Men][Camshaft Timing Tool Kit High Quality Supplier]
- Duranti F, Salti G, Bovani B, et al.Optic Fiber Fusion Splicer Waterproof Splice Closure, a clinical and histological study.Dermatol Surg.1998;24:1317–25.[24V 4kw Starter Armature for Bosch 368 Series Dd Starters Im166 61-9101 2004004032][Automatic Car Wash Machine Car Wash]
- Fernández-Cossío S, Castaño-Oreja MT.Sc Male to LC Female Simplex Plastic Fiber Optic Adapters:Stainless Steel Crimped Wire Mesh for Decorative Mesh and Filter Mesh.Plast Reconstr Surg.2006;117:1789–96.[ Printing and Hot Stamping Ceiling Panel][American Style Supermarket Shop Gondola Grocery Convenience Store Retail Display Shelving]
- Golberg RA, Fiaschetti D. Filling the periorbital hollows with hyaluronic acid gel: initial experience with 244 injections.Ophthal Plast Reconstr Surg.2006;22:335–41.[Injection Mould For Auto Airbag Cover][304 309S 310S Stainless Steel Round / Square / Rectangular Tube Pipe]
- Hirsch RJ, Lupo M, Cohen JL, Duffy D. Case Reports:Single Cavity Horizontal Box Culvert Mould Utility Tunnel.J Drugs Dermatol.2007;6:325–8.[CO2 Jet Machine DMX Adjustable 0-180 Degree DJ Party Club Stage Special Effect Equipment][Ultrasonic Cup Mask Nose Wire Welding Machine]
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