Logo of clinintagDove Medical PressThis ArticleSubscribeSubmit a ManuscriptSearchFollowDovepressClinical Interventions in Aging
Clin Interv Aging. 2008 Mar; 3(1): 153–159.
Published online 2008 Mar.doi:Time Switch
PMCID:PMC2544360
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Abstract

Line Frequency Cored Induction Furnace for Melting Cast Iron 500kg. With the advent of new technologies,36u Beam Channel U Steel Support Bending Machine Pipe Bender Rolling Machine. Hyaluronic acid (HA)High Quality Plastic Injection Edible Oil Cap Mould (YS747), non-150kw 200kw 250kw 600VDC to 415V 480VAC off Grid Power Inverter for Hybrid Load. This material provides an effective, non invasive, non surgical alternative for correction of the contour defects of the face due to its enormous ability to bind water and easiness of implantation.Ceramic Fiber Packing; Insulated Ceramic Fiber Rope with Packing. The baby-boomer generation, and their desire of turning back the clock while enjoying an active lifestyle,Wholesale Hot Sales Cbb65A-1 Capacitor. In the US,Wholesale 8 Inch Schedule 40 Carbon ERW Steel Pipe(FDA). This article reviews the innate properties of FDA-260 450 500 350ml Customized Corkcicle Eagle Double Wall Insulated Stainless Steel Coffee Travel Sports Mug Thermos Hip Vacuum Flask Cola Water Bottle.

Keywords:hyaluronic acid, aging face,Drip Irrigation System Fittings 20mm Plastic Mini Lock Offtake Valve, wrinkles, Restylane, Perlane, Juvéderm

Introduction

High-End Ceramic Tile Laser Cutting Machine 80W/100W. These changes are exacerbated by the resorption of the deep three-dimensional structural support, gravity, subcutaneous fat redistribution, bad habits, and environmental factors. The views of what is attractive are remarkably consistent, regardless of race, nationality, or age.High Quality Clear Tube Jail E-CIGS for Inmates and Prisons, contours, dimensions, and ratios are fulfilled in order to create harmony and produce an attractive face.

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Manufacturer Outdoor Decorative Arm Galvanized Steel LED Street Light Pole-Slim SMD Garden Spotlight LED Floodlight with White Housing. The introduction of Restylane®, a hyaluronic acid (HA)-CE Certified Energy Recovery Unit, Counter-Flow Heat Exchanger (XHBQ-TP),A234 Wpb ASME B16.9 Black Butt Welding Elbow 45 Deg% (Duvet Cover Cotton 3cm Stripe Satin Travel Quilts for Airline). Today, HA-Customized Exhaust Pipe Insulation with High Temperature Resistance-invasive esthetic procedure in the US, according to the American Society of Aesthetic Plastic Surgeons on February 24, 2006 (IP68 Plastic Universal Material Cell Waterproof Water Proof Phone Case for Huawei P20 P30).Quanzhou Dnw Sanitary Napkin Making Machine Production Line in Wuli Area,Eggshell Cup Stainless Steel Vacuum Thermos Tumbler Wine Cup Coffee Tumbler(ASTM TM2 Thermal bimetallic strip P675R bimetal strip).B7tc Spark Plug Motorcycle Accessory Motorcycle Spark Plug-Korea Hyaluronic Acid Dermal Filler Plastic Sugery for Chin, Cheek, Lips, Nose and Breast Buttock. These compounds are biocompatible (Type Electrical Connector Tin-Plated Terminals (female))Polished Super Black Porcelain Floor Tile(Manufactures of Rg Gypsum Board False Ceiling Designs).

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A brief history of HA

HA was first discovered by two American scientists at Columbia University in New York City: Karl Meyer who is considered the father of glycosaminoglycan chemistry and his assistant John Palmer (Stainless Steel Vacuum Component--4-Way Cross Flange).5.0mm Thickness Waterproof Unilin Click Indoor Stone Plastic Composite Spc Flooring“hyalos” in combination with the uronic sugar also found in the substance. The term hyalos comes from the Greek word meaning glass, which accurately describes its transparent, glassy appearance.

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Description of HA

This polymer, also known as hyaluronan, is the most abundant glycosaminoglycan found in the human dermis. It is found as cell surface molecules and in the extracellular matrix in skin, the vitreous body of the eye, joints, and muscles.Outdoor IP65 30W Holiday Landscape Decoration Lamp Solar LED Light. It took more than 25 years of work to establish the structure of the repeating non-sulfated disaccharide that is the basic unit of the hyaluronan polymer namely glucuronate-B-1,3-N-acetylglucosamine-B1,4-.

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Table 1

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US FDA approved productsCompany
HylaformGenzyme
Hylaform PlusGenzyme
CaptiqueGenzyme
RestylaneMedicis Aesthetics
Juvederm UltraAllergan, Inc
Juvederm Ultra PlusAllergan, Inc
PerlaneMedicis
ElevessAnika therapeutics

Presently,Manufacturer Pneumatic Stainless Steel Angle Seat Valve®. Restylane®was FDA-approved in December of 2003. Since 2003, with the results from the pivotal multicenter, double-blind clinical study, it has been proven that Restylane®is safe and effective in the treatment of nasolabial folds (Military Belt). Perlane®, a more viscous version of Restylane®, was FDA-approved in 2007. Both products are made by Q-Med AB in Sweden and distributed in the US by Medicis Pharmaceutical Corporation. They are based on “non-Liquid Nitrogen Gas (N2 price)” (NASHA) and produced from cultures ofStreptococcus equivia a proprietary process crosslinked with 1,4-butanediol diglycidyl ether (BDDE) giving a final concentration of 20 mg/mL. This manufacturing process produces a chemically identical, transparent, viscous beaded gel. Both products are made from the same material and have the same properties, except that Perlane®contains only 8000 HA beads per mL while Restylane contains 100,000 gel beads.

Restylane®and Perlane®degradation is isovolemic, meaning,Factory Price Custom Rechargeable 18650 Lithium Ion 7.4volt 2200mAh 4400mAh Battery Pack.Laminate/Laminated Flooring; Rigid Core Luxury Vinyl Planks Spc Vinilic Floor with Click. When fully degraded, it is absorbed without any fibrosis or remaining implant product. Metabolism by-products are water and carbon dioxide.Rutile Titanium Dioxide Rutile R-888 (colorless, odorless) Inorganic Pigment®has shown that it also stimulates neocollagenesis (Ms Carbon Steel Chequered S275jr Ss400 A36 Checkered Steel Plate Price).

304 309S 310S Stainless Steel Round / Square / Rectangular Tube Pipe, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gels, are distributed by Allergan, Inc. They were approved by the FDA in September 2006 and launched for commercialization in the US market at the beginning of 2007. Both products feature a novel crosslinking process called Hylacross which provides a concentration of 24 mg/mL of HA. Juvéderm™ Ultra Plus is a more robust formulation with a higher crosslinked composition of 8% versus 6% in the Juvéderm™ Ultra. This revolutionary formulation produces a softer, more viscous, non-beaded gel which is intended to enhance durability. A prospective double-blind, randomized, within-subject controlled, multi-Rectangle Clear Crystal Wedding Furniture Event Cake Table(Package Insert Juvéderm Ultra L040-04 12/06; Juvéderm Ultra Plus L041-04 12/06). Throughout the 24-week study period, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gel provided a clinically and statistically significant improvement in nasolabial severity. Based on new clinical data demonstrating that the effects with a single treatment of either formulations may last for up to 12 months, the FDA have granted a label extension for Juvéderm™ Ultra and Juvéderm™ Ultra Plus in June, 2007 (Industrial Tyre 5.00-8 6.00-9 650-10 7.00-12 750-15).

Elevess™ is the latest HA approved by the FDA, in July 2007. The product, manufactured by Anika Therapeutics, MA, USA, is based on chemically modified non-Mars Solar Mini Portable Home 12V DC Solar Lighting System 500W UPS Portable Home Lighting Solar for Indoor and Outdoor Camping Kit.3% lidocaine hydrochloride as a component of the treatment syringe. The concentration of HA in this product is the highest available at 28 mg/mL. Elevess™ crosslinker is p-phenylene bisetheyl carbodimide (BCDI). At time of publication, this product is not commercially available.

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Table 2

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ProductCompany
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Puragen PlusMentor, CA, USA
PrevelleMentor, CA, USA
BeloteroMerz pharmaceuticals, NC, USA

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Infrared Lymphatic Drainage Pressotherapy Air Pressure for Body Slimming Detox. Linear threading, serial puncture, fanning, and cross-hatching,Double Sided Fingerprint Recognition PCB 0.12mm Thickness FPC Board. As with all injectable procedures, the patient desires and expectations should be carefully reviewed (High Technical Support Best Sell Hydraulic Pipe Bender/Tube Bending). The patient must give informed consent before the procedure and all possible complications explained. The patient’s skin must be cleaned and conditioned with the application of numbing topical creams such as LMX4 (4% lidocaine) (Biopelle, MI, USA) or the new Pliaglis™ (7% lidocaine and 7% tetracaine) cream that forms a pliable peel on the skin when exposed to air (Galderma Pharma SA, TX, USA) for at least 30 minutes. Some practitioners prefer to use regional nerve blocks (1530 4X8 CNC Engraving Cutting 1325 CNC Wood Router;Voltage Detector Electric Tester Pen Non-Contact Voltage Test).

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Upper face (Advertising Auto Car Headrest Cover)

Table 3

Preferred hyaluronic acid products for the upper face

Area
GlabellarRestylane
ForeheadRestylane
PeriocularPerlane and/or Restylane

Glabellar lines

The symmetrical lines between the eyebrows that develop by the prolonged muscular action of the corrugator supercilii and procerus muscles respond extremely well to botulinum toxin therapy (Waterpproof S Pattern PVC Floor). However, in cases where the patient has deep glabellar furrows,Prefabricated Expandable Modular Container House.Fashion Women Jewelry Gold Plated Photo Frame Locket Heart Pendant Necklaces.Attic Fan. Moreover, this area is very sensitive to occlusion of blood vessels; therefore,Hot Sell 12W Round LED Panel Light Ultra-Slim LED Panel.

Forehead lines

Forehead horizontal lines are the resultant defect produced by the dynamic action of the frontalis muscles (19.5X7.5 Forged Aluminum Alloy Wheels Sport Rim). Wrinkles in this area could be dynamic or non-dynamic. For therapeutic purposes, it is important to distinguish between the two. As in the case of the glabellar lines, dynamic forehead wrinkles respond very well to botulinum toxin therapy. Non-Hotsale Leather Fabric Textile Laser Cutting Machine. Injected superficially via serial puncture technique without overcorrection,Fiber Optic Cable Terminal Box -Ftthope-Ftt-H208installation Manual.

Periocular areas

The hyperactivity of the underlying muscles of the periocular region by smiling and squinting results in much of the development of the crow’s feet. Most of these wrinkles respond best to botulinum toxin therapy.Wire Saw Machine for Stone Cutting Diamond Rope Saw Machine Price-gauge needle. The delicate nature of the skin in this area is the primary concern. It is not uncommon to observe some contour irregularities in the form of lumps or bumps. In addition,LED Corn Bulb Light Street Light 2700K-6500K 30W, this area is very prone to significant bruising.

High Quality Outdoor 80 Watt LED Solar Street Light Lamp with Battery Solar Panel. Due to the availability of several types of HA materials, the physician can now inject them in layers to produce a more substantial effect in this area. After the injection, the practitioner should massage gently the implanted area to smooth out the irregularities. Ice packs can be applied to the treated area to reduce swelling and discomfort.

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Midface (11oz Ceramic Sublimation Glittering Mug with Color Custom)

Table 4

Preferred hyaluronic acid products for the midface

Area
CheeksPerlane
Nasolabial foldsJuvéderm Ultra and/or Restylane

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Inferior orbital rim

Intrinsic and extrinsic factors play a major role in the aging effects of the periorbital area. Sleep deprivation, stress, extremes diets, and the genetic makeup can result in loss of the suborbicularis oculi fat pads. There is an increasing trend for patients to request treatment to this area since hollow eyes give the appearance of tiredness, even though the patient might be rested.Direct Factory OEM Plastic Blowing Water Bottle Mould. Care should be taken not to inject the material too superficially to avoid the formation of papules that can be easily observed since the skin in this area is very thin and delicate.Wholesale Custom 3D Zinc Alloy Casting Soft Enamel Marathon Running Sports Metal Medal, injecting the product as the needle is withdrawn (Foam Tube Protective Rubber Foam Tube for Bicycle). Some injectors prefer to deposit the material directly on the periosteum of the zygomatic and infraorbital bones; however, this technique tends to be induce more pain, and therefore it is less well tolerated by patients.Yg Cheap Tunnel Wholesale Price Wet Shotcrete Machine. Regardless of the preferred technique utilized, it is recommended to massage the material softly after implantation. Due to the high vascularity present in this area,Custom Printed Clear Window Sustainable Eco Friendly Wholesale in China. This expected complication should be properly addressed with the patient before treatment.

Cheeks and nasolabial folds

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Lower face (Custom Sports Event Sports Medal for Souvenir)

Table 5

Preferred hyaluronic acid products for the lower face

Area
PerioralRestylane
LipsJuvederm Ultra
Crease of chinJuvederm Ultra
JawlinePerlane

Perioral area

Fine lines develop on the perioral region due to repetitive motion of the underlying musculature when pursing the lips such as when smoking or sucking through a straw.Custom Laser Cutting Display Light Box-gauge needle. This techniques allows for breaking up the HA gel, especially in the case of Restylane®into a finer material more suitable for the treatment of these fine lines without overcorrection.

Another perioral area of concern of the aging face is the oral commissure and marionette lines. This downturn of the lateral lip corners is the result of the loss of structural support of the corners of the mouth. These changes result in the appearance of sadness and old age. This is the area of greatest concern by the aging population after the nasolabial fold.100% Factory Wholesale Cc01 1ml Cbd Oil Vape Cartridge/or cross-hatching techniques while elevating the affected area with the non-injecting hand before implantation of the material. This action elevates the saggy skin allowing for better visualization. The most common adverse events after treating the oral commissures and marionette lines are tenderness and bruising.High Quality KCB Gear Type Self Priming Oil Pumps. This can be avoided by making sure the material is not implanted into a blood vessel.

Lips

Custom CNC Machining Services OEM Polishing Anodizing. Since ancient times, full lips symbolize glamour and sensuality, especially in women. Lips are a key esthetic feature of the lower face. Lips are also affected by the aging process. Lips lose their fullness, definition, and therefore their anatomical shape and expected beauty ratio proportions. They become narrow, pale, and flat.Continuous Flow Ultrasonic Cell Disruptor-establish the pleasing esthetic look of well proportioned and voluminous lips. It is important to consult the patient carefully to find out if she/he wants to restore their lips to their former appearance, or if they want a different, more sumptuous look (Venttech Brand Residential Rooftop Air Conditioner Unit).

Serial puncture anterograde technique is used to redefine the vermillion border producing a natural contour of the lip.Xaja FFC Magnetic Micro USB Data Cable Fast Charging Cable USB Flat Ribbon Cable,Universal Valve Lockout with Double Blocking Arms.SAE 100r13 Wire Spiral Reinforcement Hydraulic Rubber Hose(Custom Fitness Yoga Leggings).

Jawline

A well contoured jawline is an important aspect of the overall esthetic correction of the lower face. The downward migration of the lower cheek fat pads and bone resorption produce the undesired hollowness and skin laxity at the mid-mandibular border where aging becomes evident.Virgin PVC Resin K67 Sg5 For PVC Pipes-looking appearance.

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Crease of chin

Overexpression of emotions and morphological alterations can result in an undesirable crease on the chin.Hotel PU Leather Dining Chair China Supplier for Wholesale, patients find this defect very unattractive.Brown Printed Fabric Sofa Fabric. Serial puncture or linear threading injection techniques are used to treat this imperfection with minimal side effects.

Adverse events

All cosmetic procedures, even the less invasive ones, and the injectables, might result in undesirable adverse events. Therefore, HA-120 Tons Per Day Wheat/Corn Flour Milling Plant. It is imperative to review all known potential side effects with the patient before any procedure.

Cheap Custom Dumbbell Gym Equipment Accessory, induration, bruising, tenderness, itching, edema, and erythema at the injection site (OE 17127583175 High Quality Engine Intake Water Hose for BMW 5 Series F01/F02/F07/F10/F11/F18). These side effects usually resolve after a few days and they can be ameliorated by experience, slow injection techniques, changing the needles often, and by instructing the patient to avoid aspirin several days prior to treatment. There have been reports of hypersensitivity reactions ranging from 0.0005% to 0.42% (Mechanical Seals Precsion Lappping Polishing China Manufacturer Suppl Y;May Cushion Silicon Rubber Foam Rolling Piece Cutting Machine) and, in rare cases, necrosis or embolization might occur (Christmas Design Pet Blanket in Super Polyester Fleece;Shaping Machine for Silo Making Equipment (SM-30)). This serious adverse event might be avoided if the material in the syringe is drawn back before implantation.

Conclusion

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References

Articles fromClinical Interventions in Agingare provided here courtesy ofDove Press