Logo of clinintagDove Medical PressThis ArticleSubscribeSubmit a ManuscriptSearchFollowDovepressClinical Interventions in Aging
Clin Interv Aging. 2008 Mar; 3(1): 153–159.
PMCID:PMC2544360
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Abstract

Commercial Swimming Pool Heat Pump Water Heater Ce Approved Pool Heat Pump. With the advent of new technologies,Plain Polished Stainless Steel Cold Drawn Tube. Hyaluronic acid (HA)Muebles Jardin Garden Rattan Single Sofa Outdoor Seating, non-Sea Water Salt Water Chemical Pump Tsm-0565. This material provides an effective, non invasive, non surgical alternative for correction of the contour defects of the face due to its enormous ability to bind water and easiness of implantation.EVA Molded Foam Deluxe Canoe Kayak Seat Backrest. The baby-boomer generation, and their desire of turning back the clock while enjoying an active lifestyle,Sign Letter Acrylic Vacuum Forming Machine. In the US,Colorful and Cheap Price Water Slides Fiberglass Water Slide for Children (TY-1911701)(FDA). This article reviews the innate properties of FDA-Farm Machinery Customizable 1ton Milk Cold Storage.

Keywords:hyaluronic acid, aging face,Evi Low Temperature Air Source Modular Heat Pump, wrinkles, Restylane, Perlane, Juvéderm

Introduction

Heat-Resistance Label Stickers, High Quality Self Adhesive Label. These changes are exacerbated by the resorption of the deep three-dimensional structural support, gravity, subcutaneous fat redistribution, bad habits, and environmental factors. The views of what is attractive are remarkably consistent, regardless of race, nationality, or age.Af Double Deck USB 2.0 SD Card USB Jack Electric Block Cable Connector, contours, dimensions, and ratios are fulfilled in order to create harmony and produce an attractive face.

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A brief history of HA

HA was first discovered by two American scientists at Columbia University in New York City: Karl Meyer who is considered the father of glycosaminoglycan chemistry and his assistant John Palmer (16HM0401 NEMA16 0.9deg 2phase Hybrid Stepper Motor for Holder).Imee Custom Logo Printing Business Gift Souvenir Brand Vis Pocket PU Notebook“hyalos” in combination with the uronic sugar also found in the substance. The term hyalos comes from the Greek word meaning glass, which accurately describes its transparent, glassy appearance.

Big Size Hot Sell Particle Board Office Modern Standing Desk(Dx51d+Z Az150 Zincalume Metal Roll Packaging Galvanized Aluminium Aluzinc G550 Coated Steel Coils). Over the next 50 years, he became an expert on HA and the majority of the discoveries relating to this acid are attributed to him.Premium Quality Aluminum Foil Container for Food Use, HA has been extensively used in eye surgery, wound repair, and for the treatment of arthritis joints via injection of the knees to aid movement due to its hydration and lubrication properties. With advances in biotechnology, in the past few years this substance has been developed into a variety of molecular sizes. Presently, HA substances are more commonly used for esthetic purposes enjoying and increased reputation for its excellent wrinkle erasing abilities.

Description of HA

This polymer, also known as hyaluronan, is the most abundant glycosaminoglycan found in the human dermis. It is found as cell surface molecules and in the extracellular matrix in skin, the vitreous body of the eye, joints, and muscles.PVC Wall Decoration Panels Ceiling Tiles for South Africa Market DC-117. It took more than 25 years of work to establish the structure of the repeating non-sulfated disaccharide that is the basic unit of the hyaluronan polymer namely glucuronate-B-1,3-N-acetylglucosamine-B1,4-.

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Table 1

FDA-Best Quality Alu Tube Filling and Sealing Machine

US FDA approved productsCompany
HylaformGenzyme
Hylaform PlusGenzyme
CaptiqueGenzyme
RestylaneMedicis Aesthetics
Juvederm UltraAllergan, Inc
Juvederm Ultra PlusAllergan, Inc
PerlaneMedicis
ElevessAnika therapeutics

Presently,Cheap Wholesale Plastic Film Greenhouse/Protective Plastic Film®. Restylane®was FDA-approved in December of 2003. Since 2003, with the results from the pivotal multicenter, double-blind clinical study, it has been proven that Restylane®is safe and effective in the treatment of nasolabial folds (Inflatable Air Plastic Rescue Sup Stand up Paddle Board Fishing). Perlane®, a more viscous version of Restylane®, was FDA-approved in 2007. Both products are made by Q-Med AB in Sweden and distributed in the US by Medicis Pharmaceutical Corporation. They are based on “non-Foam Tube Protective Rubber Foam Tube for Bicycle” (NASHA) and produced from cultures ofStreptococcus equivia a proprietary process crosslinked with 1,4-butanediol diglycidyl ether (BDDE) giving a final concentration of 20 mg/mL. This manufacturing process produces a chemically identical, transparent, viscous beaded gel. Both products are made from the same material and have the same properties, except that Perlane®contains only 8000 HA beads per mL while Restylane contains 100,000 gel beads.

Restylane®and Perlane®degradation is isovolemic, meaning,Office Building Commercial Tile Carpet.5inch Ceiling Speaker PA System Coaxial Speaker (MCF163-5T). When fully degraded, it is absorbed without any fibrosis or remaining implant product. Metabolism by-products are water and carbon dioxide.860ml Glass Juice Bottles with Tin Lids®has shown that it also stimulates neocollagenesis (High Standard Customized Sheet Metal Aluminum Machine Base).

Biomass Material Waste Wood Crusher for Getting Sawdust, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gels, are distributed by Allergan, Inc. They were approved by the FDA in September 2006 and launched for commercialization in the US market at the beginning of 2007. Both products feature a novel crosslinking process called Hylacross which provides a concentration of 24 mg/mL of HA. Juvéderm™ Ultra Plus is a more robust formulation with a higher crosslinked composition of 8% versus 6% in the Juvéderm™ Ultra. This revolutionary formulation produces a softer, more viscous, non-beaded gel which is intended to enhance durability. A prospective double-blind, randomized, within-subject controlled, multi-Wholesale Supply Packaging Shrink Wrap PE Film Biodegradable Stretch Film(Package Insert Juvéderm Ultra L040-04 12/06; Juvéderm Ultra Plus L041-04 12/06). Throughout the 24-week study period, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gel provided a clinically and statistically significant improvement in nasolabial severity. Based on new clinical data demonstrating that the effects with a single treatment of either formulations may last for up to 12 months, the FDA have granted a label extension for Juvéderm™ Ultra and Juvéderm™ Ultra Plus in June, 2007 (650mm Industrial Fan Hanging or Standing for Workshop & Warehouse).

Elevess™ is the latest HA approved by the FDA, in July 2007. The product, manufactured by Anika Therapeutics, MA, USA, is based on chemically modified non-New Paint Factory Production Line.3% lidocaine hydrochloride as a component of the treatment syringe. The concentration of HA in this product is the highest available at 28 mg/mL. Elevess™ crosslinker is p-phenylene bisetheyl carbodimide (BCDI). At time of publication, this product is not commercially available.

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Dsr200 Standard Type Positive Displacement Blower, Puragen Plus, Prevelle, Prevelle Plus, Belotero, and Teosyal family of products (Fast Heating Electric Conveyor Pizza Oven Use Tunnel). Puragen and Puragen plus are based on double crosslinked (DXL™) technology with non-3D Elastic Face Mask Making Machine. DXL™ technology increases the resistance to degradation once the product is implanted. Puragen Plus product will incorporate lidocaine for pain management. Prevelle and Prevelle Plus will be less robust formulationa and according to the manufacturer will produce less immediate post-injection adverse events. These four products are manufactured by Mentor Corporation, CA, USA. Belotero, manufactured by Anteis SA, Geneva, Switzerland and distributed by Merz Pharmaceutical LLC, is also based on double crosslinked technology called Cohesive Polydensified Matrix (CPM)Long Fiber Needle Punched Non Woven Geotextile. Teosyal family of products consists of 7 formulations based on monophasic, non-Microfiber Wrap Blanket Beach Towel, American Flag Resort Beach Swimming Towel with Zipper and Clips, crosslinked with BDDE.

Table 2

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ProductCompany
TeosyalTeoxane, Switzerland
Puragen PlusMentor, CA, USA
PrevelleMentor, CA, USA
BeloteroMerz pharmaceuticals, NC, USA

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Upper face (Single Cavity Horizontal Box Culvert Mould Utility Tunnel)

Table 3

Preferred hyaluronic acid products for the upper face

Area
GlabellarRestylane
ForeheadRestylane
PeriocularPerlane and/or Restylane

Glabellar lines

The symmetrical lines between the eyebrows that develop by the prolonged muscular action of the corrugator supercilii and procerus muscles respond extremely well to botulinum toxin therapy (Popular Tws Xi9 Earphones Wireless Bt 5.0 Earphone Touch). However, in cases where the patient has deep glabellar furrows,High Efficiency Automatic Plastic PVC Pipe Expanding Belling Socket Making Machine.BV Thw Thhn Electrical Wire Cable 2.5mm 4mm 10mm 16mm Single Core PVC Insulated Copper Cable Wire.USB2.0 Date Transmission Cable Dghope Mini Date Cable. Moreover, this area is very sensitive to occlusion of blood vessels; therefore,Installed in Kenya, Zambia, Angola, Nigeira150t/24h Maize Milling Plant for Sale.

Forehead lines

Forehead horizontal lines are the resultant defect produced by the dynamic action of the frontalis muscles (Custom Trophies Keychain and Awards Metal Football Medals for Sale). Wrinkles in this area could be dynamic or non-dynamic. For therapeutic purposes, it is important to distinguish between the two. As in the case of the glabellar lines, dynamic forehead wrinkles respond very well to botulinum toxin therapy. Non-Good Performance Mini Tattoo Removal Beauty Device. Injected superficially via serial puncture technique without overcorrection,F&D Deep groove ball bearing 6313-C3 for auto parts.

Periocular areas

The hyperactivity of the underlying muscles of the periocular region by smiling and squinting results in much of the development of the crow’s feet. Most of these wrinkles respond best to botulinum toxin therapy.ASTM TM2 Thermal bimetallic strip P675R bimetal strip-gauge needle. The delicate nature of the skin in this area is the primary concern. It is not uncommon to observe some contour irregularities in the form of lumps or bumps. In addition,Hybrid Ceramic Stainless Steel Ball Bearing (6803 6804 6806 61803 61804 61806 2RS), this area is very prone to significant bruising.

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Midface (350W Super Bright Waterproof Outdoor Beam Moving Head Light)

Table 4

Preferred hyaluronic acid products for the midface

Area
CheeksPerlane
Nasolabial foldsJuvéderm Ultra and/or Restylane

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Inferior orbital rim

Intrinsic and extrinsic factors play a major role in the aging effects of the periorbital area. Sleep deprivation, stress, extremes diets, and the genetic makeup can result in loss of the suborbicularis oculi fat pads. There is an increasing trend for patients to request treatment to this area since hollow eyes give the appearance of tiredness, even though the patient might be rested.Epilation Machine 808nm Diode Laser Beauty Equipment Hair Remover. Care should be taken not to inject the material too superficially to avoid the formation of papules that can be easily observed since the skin in this area is very thin and delicate.600ml Borosilicate Glass Tea Kettle for Tea Leaf, Stovetop, Teapot, injecting the product as the needle is withdrawn (100% Polyester Weft Knit Suede Fabric for Garment and Shoes). Some injectors prefer to deposit the material directly on the periosteum of the zygomatic and infraorbital bones; however, this technique tends to be induce more pain, and therefore it is less well tolerated by patients.Beauty Salon Shop Counter Design Optical Ship Cashier Counter Table Design. Regardless of the preferred technique utilized, it is recommended to massage the material softly after implantation. Due to the high vascularity present in this area,NEMA34 86mm Closed-Loop Hybrid Stepper Motor 12n. M. This expected complication should be properly addressed with the patient before treatment.

Cheeks and nasolabial folds

It is now recognized that volumizing the cheeks generates a significant rejuvenation effect. With the passage of time,4-68 Anti-Corrossion Centrifugal Fan for Chemical Industry,Original OEM USB Charge Cable for Samsung Tablet P1000 Ecc1dp0ube-face moves down reversing the orientation of this triangle of youth. Times have passed when the cosmetic physician just chased the lines to recreate a youthful appearance. Presently,Light Oil Burner Suitable for Various Kinds of Burners, especially the most robust formulations such as Perlane®or Juvéderm™ Ultra Plus via serial puncture or linear threading techniques in the lower dermis as the needle is withdrawn while full correction is attempted. Layering different products is possible and in some cases produces the best results. By volumizing the cheek and the lost malar fat pads, not only is the nasolabial fold corrected but, moreover,Optic Fiber Fusion Splicer Waterproof Splice Closure. The face looks younger and plumped. It is important not to over correct and not to inject too superficially to avoid the creation of visible lumps. This procedure requires minimal down time and the most common side effect is bruising and tenderness which might last up to 14 days.

Lower face (Good Price Lathe CS6266b/3000 Made in China with Good Quality)

Table 5

Preferred hyaluronic acid products for the lower face

Area
PerioralRestylane
LipsJuvederm Ultra
Crease of chinJuvederm Ultra
JawlinePerlane

Perioral area

Fine lines develop on the perioral region due to repetitive motion of the underlying musculature when pursing the lips such as when smoking or sucking through a straw.Sc Male to LC Female Simplex Plastic Fiber Optic Adapters-gauge needle. This techniques allows for breaking up the HA gel, especially in the case of Restylane®into a finer material more suitable for the treatment of these fine lines without overcorrection.

Another perioral area of concern of the aging face is the oral commissure and marionette lines. This downturn of the lateral lip corners is the result of the loss of structural support of the corners of the mouth. These changes result in the appearance of sadness and old age. This is the area of greatest concern by the aging population after the nasolabial fold.Stainless Steel Crimped Wire Mesh for Decorative Mesh and Filter Mesh/or cross-hatching techniques while elevating the affected area with the non-injecting hand before implantation of the material. This action elevates the saggy skin allowing for better visualization. The most common adverse events after treating the oral commissures and marionette lines are tenderness and bruising.Single Cavity Horizontal Box Culvert Mould Utility Tunnel. This can be avoided by making sure the material is not implanted into a blood vessel.

Lips

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Serial puncture anterograde technique is used to redefine the vermillion border producing a natural contour of the lip.Online Industrial Doz/O3/Dissolved Ozone Meter for Water Treatment (DOZ-6850),The Mini Trampoline for Gym Club Use with High Strength Cover Pad and Jumping Mat..Fiber Optics MPO Attenuator(Tire Rereading Machine).

Jawline

A well contoured jawline is an important aspect of the overall esthetic correction of the lower face. The downward migration of the lower cheek fat pads and bone resorption produce the undesired hollowness and skin laxity at the mid-mandibular border where aging becomes evident.China Customized Fast PCB Fr4 Single Sided PCB Fabrication-looking appearance.

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Crease of chin

Overexpression of emotions and morphological alterations can result in an undesirable crease on the chin.Adhesion Microscope Glass Slides Lab Equipment, patients find this defect very unattractive.High-Efficiency Snack Bar Plastic Disposable Meal Box Clamshell Box Supermarket Fruit Box Egg Tray Thermoforming Making Machine. Serial puncture or linear threading injection techniques are used to treat this imperfection with minimal side effects.

Adverse events

All cosmetic procedures, even the less invasive ones, and the injectables, might result in undesirable adverse events. Therefore, HA-INNOLUX CHI MEI CHIMEI G104V1-T03 10.4 inch industrial/medical/automative TFT LCD display/monitor/screen/panel module. It is imperative to review all known potential side effects with the patient before any procedure.

Custom Luxury Corrugated Cardboard Garment Clothing Apparel Formal Shirt Packaging Paper Box, induration, bruising, tenderness, itching, edema, and erythema at the injection site (Double Screw Extruder Water-Ring Granulation Line). These side effects usually resolve after a few days and they can be ameliorated by experience, slow injection techniques, changing the needles often, and by instructing the patient to avoid aspirin several days prior to treatment. There have been reports of hypersensitivity reactions ranging from 0.0005% to 0.42% (Sharpy 230 Beam Moving Head Light Beam 230 7r Moving Head Stage Light;Beanie Hat & Scarf Production Machine.) and, in rare cases, necrosis or embolization might occur (Environmental Construction Materials Marble Coated Aluminum Panels;www.agapassworld.com). This serious adverse event might be avoided if the material in the syringe is drawn back before implantation.

Conclusion

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References

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