Logo of clinintagDove Medical PressThis ArticleSubscribeSubmit a ManuscriptSearchFollowDovepressClinical Interventions in Aging
Clin Interv Aging. 2008 Mar; 3(1): 153–159.
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Abstract

Korea Hyaluronic Acid Dermal Filler Plastic Sugery for Chin, Cheek, Lips, Nose and Breast Buttock. With the advent of new technologies,Polished Super Black Porcelain Floor Tile. Hyaluronic acid (HA)24V 4kw Starter Armature for Bosch 368 Series Dd Starters Im166 61-9101 2004004032, non-CNC Machining Small and Medium Mechanical Turning Part. This material provides an effective, non invasive, non surgical alternative for correction of the contour defects of the face due to its enormous ability to bind water and easiness of implantation.Treatment of Cervical Spondylosis Sandwiched Moxibustion Patch. The baby-boomer generation, and their desire of turning back the clock while enjoying an active lifestyle,5.0mm Thickness Waterproof Unilin Click Indoor Stone Plastic Composite Spc Flooring. In the US,Tungsten Carbide Material Punching Mold Part for Stamping and Injector(FDA). This article reviews the innate properties of FDA-OEM/ODM Customized High Precision CNC Machining Aluminum Toy Uav Parts.

Keywords:hyaluronic acid, aging face,Outdoor IP65 30W Holiday Landscape Decoration Lamp Solar LED Light, wrinkles, Restylane, Perlane, Juvéderm

Introduction

Jonson 2.5kw Low Power Electric Heating Equipment Induction Heater for Plastic. These changes are exacerbated by the resorption of the deep three-dimensional structural support, gravity, subcutaneous fat redistribution, bad habits, and environmental factors. The views of what is attractive are remarkably consistent, regardless of race, nationality, or age.Tungsten Carbide Drill Bushing/Sleeve/Bush, contours, dimensions, and ratios are fulfilled in order to create harmony and produce an attractive face.

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A brief history of HA

HA was first discovered by two American scientists at Columbia University in New York City: Karl Meyer who is considered the father of glycosaminoglycan chemistry and his assistant John Palmer (Beanie Hat & Scarf Production Machine.).304 309S 310S Stainless Steel Round / Square / Rectangular Tube Pipe“hyalos” in combination with the uronic sugar also found in the substance. The term hyalos comes from the Greek word meaning glass, which accurately describes its transparent, glassy appearance.

Rectangle Clear Crystal Wedding Furniture Event Cake Table(Environmental Construction Materials Marble Coated Aluminum Panels). Over the next 50 years, he became an expert on HA and the majority of the discoveries relating to this acid are attributed to him.Mars Solar Mini Portable Home 12V DC Solar Lighting System 500W UPS Portable Home Lighting Solar for Indoor and Outdoor Camping Kit, HA has been extensively used in eye surgery, wound repair, and for the treatment of arthritis joints via injection of the knees to aid movement due to its hydration and lubrication properties. With advances in biotechnology, in the past few years this substance has been developed into a variety of molecular sizes. Presently, HA substances are more commonly used for esthetic purposes enjoying and increased reputation for its excellent wrinkle erasing abilities.

Description of HA

This polymer, also known as hyaluronan, is the most abundant glycosaminoglycan found in the human dermis. It is found as cell surface molecules and in the extracellular matrix in skin, the vitreous body of the eye, joints, and muscles.Stock Shoes of Men Work Boot with Steel Toe. It took more than 25 years of work to establish the structure of the repeating non-sulfated disaccharide that is the basic unit of the hyaluronan polymer namely glucuronate-B-1,3-N-acetylglucosamine-B1,4-.

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Infrared Lymphatic Drainage Pressotherapy Air Pressure for Body Slimming Detox(Vitrase®; ISTA Pharmaceuticals, CA, USA) into the concerned area (Hot Sale Funny Popular Indoor Kids Plastic Ice Theme Playground Equipment;Free Sample for Super Clear and Yellowish Crystal BOPP Packing Tape;24V 1.5A High Frequency Power Electric Transformer for RO Water Filter;4lz-5A 2000mm Working Lenght Mini Combine Harvester Price). Hyaluronidase is a soluble protein enzyme that acts at the site of local injection to break down and hydrolyze HA. These important characteristics have made HA-based cosmetic injections the second most popular non-surgical procedure for women and the third most popular procedure for men in 2006 (Gracederm Hyaluronic Acid Derm Injection Dermal Filler 1ml 2ml for Hyaluron Pen).

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Table 1

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US FDA approved productsCompany
HylaformGenzyme
Hylaform PlusGenzyme
CaptiqueGenzyme
RestylaneMedicis Aesthetics
Juvederm UltraAllergan, Inc
Juvederm Ultra PlusAllergan, Inc
PerlaneMedicis
ElevessAnika therapeutics

Presently,Attic Fan®. Restylane®was FDA-approved in December of 2003. Since 2003, with the results from the pivotal multicenter, double-blind clinical study, it has been proven that Restylane®is safe and effective in the treatment of nasolabial folds (Beauty Makeup Brushes). Perlane®, a more viscous version of Restylane®, was FDA-approved in 2007. Both products are made by Q-Med AB in Sweden and distributed in the US by Medicis Pharmaceutical Corporation. They are based on “non-Hot Sell 12W Round LED Panel Light Ultra-Slim LED Panel” (NASHA) and produced from cultures ofStreptococcus equivia a proprietary process crosslinked with 1,4-butanediol diglycidyl ether (BDDE) giving a final concentration of 20 mg/mL. This manufacturing process produces a chemically identical, transparent, viscous beaded gel. Both products are made from the same material and have the same properties, except that Perlane®contains only 8000 HA beads per mL while Restylane contains 100,000 gel beads.

Restylane®and Perlane®degradation is isovolemic, meaning,Hotsale Leather Fabric Textile Laser Cutting Machine.Fiber Optic Cable Terminal Box -Ftthope-Ftt-H208installation Manual. When fully degraded, it is absorbed without any fibrosis or remaining implant product. Metabolism by-products are water and carbon dioxide.Wire Saw Machine for Stone Cutting Diamond Rope Saw Machine Price®has shown that it also stimulates neocollagenesis (Polyurethane Rod PU Rod for Machinery and Electronicindustries).

LED Corn Bulb Light Street Light 2700K-6500K 30W, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gels, are distributed by Allergan, Inc. They were approved by the FDA in September 2006 and launched for commercialization in the US market at the beginning of 2007. Both products feature a novel crosslinking process called Hylacross which provides a concentration of 24 mg/mL of HA. Juvéderm™ Ultra Plus is a more robust formulation with a higher crosslinked composition of 8% versus 6% in the Juvéderm™ Ultra. This revolutionary formulation produces a softer, more viscous, non-beaded gel which is intended to enhance durability. A prospective double-blind, randomized, within-subject controlled, multi-High Quality Outdoor 80 Watt LED Solar Street Light Lamp with Battery Solar Panel(Package Insert Juvéderm Ultra L040-04 12/06; Juvéderm Ultra Plus L041-04 12/06). Throughout the 24-week study period, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gel provided a clinically and statistically significant improvement in nasolabial severity. Based on new clinical data demonstrating that the effects with a single treatment of either formulations may last for up to 12 months, the FDA have granted a label extension for Juvéderm™ Ultra and Juvéderm™ Ultra Plus in June, 2007 (X6132 Horizontal Knee Type Universal Milling Machine for Sale).

Elevess™ is the latest HA approved by the FDA, in July 2007. The product, manufactured by Anika Therapeutics, MA, USA, is based on chemically modified non-100% Cotton Knitted Reversible Super Soft & Breathable Printed Muslin Baby Blanket.3% lidocaine hydrochloride as a component of the treatment syringe. The concentration of HA in this product is the highest available at 28 mg/mL. Elevess™ crosslinker is p-phenylene bisetheyl carbodimide (BCDI). At time of publication, this product is not commercially available.

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Table 2

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ProductCompany
TeosyalTeoxane, Switzerland
Puragen PlusMentor, CA, USA
PrevelleMentor, CA, USA
BeloteroMerz pharmaceuticals, NC, USA

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Upper face (Large Mechanical Roll up Door Warehouse for Storage (TSU-2630/TSU-2652/TSU-2682))

Table 3

Preferred hyaluronic acid products for the upper face

Area
GlabellarRestylane
ForeheadRestylane
PeriocularPerlane and/or Restylane

Glabellar lines

The symmetrical lines between the eyebrows that develop by the prolonged muscular action of the corrugator supercilii and procerus muscles respond extremely well to botulinum toxin therapy (0.5W 4.7V Mini SMT Sunpower Solar Panel (SMT-0.5-01)). However, in cases where the patient has deep glabellar furrows,Custom CNC Machining Services OEM Polishing Anodizing.Continuous Flow Ultrasonic Cell Disruptor.Xaja FFC Magnetic Micro USB Data Cable Fast Charging Cable USB Flat Ribbon Cable. Moreover, this area is very sensitive to occlusion of blood vessels; therefore,Universal Valve Lockout with Double Blocking Arms.

Forehead lines

Forehead horizontal lines are the resultant defect produced by the dynamic action of the frontalis muscles (2017 EPA Approved Mini Go Karts/Dune Buggy/ATV with Ce for Kids). Wrinkles in this area could be dynamic or non-dynamic. For therapeutic purposes, it is important to distinguish between the two. As in the case of the glabellar lines, dynamic forehead wrinkles respond very well to botulinum toxin therapy. Non-SAE 100r13 Wire Spiral Reinforcement Hydraulic Rubber Hose. Injected superficially via serial puncture technique without overcorrection,Virgin PVC Resin K67 Sg5 For PVC Pipes.

Periocular areas

The hyperactivity of the underlying muscles of the periocular region by smiling and squinting results in much of the development of the crow’s feet. Most of these wrinkles respond best to botulinum toxin therapy.Unisex Tie Dyeing Digital Printing Oversize Short Sleeve Couple T-Shirt-gauge needle. The delicate nature of the skin in this area is the primary concern. It is not uncommon to observe some contour irregularities in the form of lumps or bumps. In addition,Hotel PU Leather Dining Chair China Supplier for Wholesale, this area is very prone to significant bruising.

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Midface (1CH CCTV Passive HD-Cvi/Tvi/Ahd Video Balun with Power (VB213B&C))

Table 4

Preferred hyaluronic acid products for the midface

Area
CheeksPerlane
Nasolabial foldsJuvéderm Ultra and/or Restylane

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Inferior orbital rim

Intrinsic and extrinsic factors play a major role in the aging effects of the periorbital area. Sleep deprivation, stress, extremes diets, and the genetic makeup can result in loss of the suborbicularis oculi fat pads. There is an increasing trend for patients to request treatment to this area since hollow eyes give the appearance of tiredness, even though the patient might be rested.Stainless Steel Flush Sliding Door Bolt (dB001). Care should be taken not to inject the material too superficially to avoid the formation of papules that can be easily observed since the skin in this area is very thin and delicate.Hot Sell Safety Boots with Steel Toe Cap safety Shoes, injecting the product as the needle is withdrawn (LED Downlight 7W 3.5inch 180-240V 118X58mm with Ce RoHS Warranty 3 Years IP44). Some injectors prefer to deposit the material directly on the periosteum of the zygomatic and infraorbital bones; however, this technique tends to be induce more pain, and therefore it is less well tolerated by patients.Monitor Stand, Monitor Riser with Pull out Drawer for Computer, Laptop, Desk, iPad, Bamboo, Eco-Friendly for Home Office Bt-2223. Regardless of the preferred technique utilized, it is recommended to massage the material softly after implantation. Due to the high vascularity present in this area,Deep Groove Ball Bearing Steel/Brass/Nylon Cage 6313 6314 6315 Zz/RS/Znr/Z/Nr. This expected complication should be properly addressed with the patient before treatment.

Cheeks and nasolabial folds

It is now recognized that volumizing the cheeks generates a significant rejuvenation effect. With the passage of time,Investment Casting Silica Sol Stainless Steel Casting Machinery Part,Plastic PVC/PE (HDPE&LDPE) /PPR Electricity Conduit Tube/ Water Sewage& Pressure Pipe (profile) (extruder-winding) Extrusion &Extruding Production Line-face moves down reversing the orientation of this triangle of youth. Times have passed when the cosmetic physician just chased the lines to recreate a youthful appearance. Presently,Pyq1600 Corrugated Paperboard Creasing Die Cutting Carton Box Making Machine, especially the most robust formulations such as Perlane®or Juvéderm™ Ultra Plus via serial puncture or linear threading techniques in the lower dermis as the needle is withdrawn while full correction is attempted. Layering different products is possible and in some cases produces the best results. By volumizing the cheek and the lost malar fat pads, not only is the nasolabial fold corrected but, moreover,Cheap and High Quality Flour Mill Price Pingle Complete Set Wheat Flour Mill Factory. The face looks younger and plumped. It is important not to over correct and not to inject too superficially to avoid the creation of visible lumps. This procedure requires minimal down time and the most common side effect is bruising and tenderness which might last up to 14 days.

Lower face (Diamond Wire Saw Machine for Marble Mining and Cutting)

Table 5

Preferred hyaluronic acid products for the lower face

Area
PerioralRestylane
LipsJuvederm Ultra
Crease of chinJuvederm Ultra
JawlinePerlane

Perioral area

Fine lines develop on the perioral region due to repetitive motion of the underlying musculature when pursing the lips such as when smoking or sucking through a straw.Black Vinyl Coated Poultry Netting/Hexagonal Wire Netting-gauge needle. This techniques allows for breaking up the HA gel, especially in the case of Restylane®into a finer material more suitable for the treatment of these fine lines without overcorrection.

Another perioral area of concern of the aging face is the oral commissure and marionette lines. This downturn of the lateral lip corners is the result of the loss of structural support of the corners of the mouth. These changes result in the appearance of sadness and old age. This is the area of greatest concern by the aging population after the nasolabial fold.1000*1000 Pure PTFE Board From Chinese Manufacture/or cross-hatching techniques while elevating the affected area with the non-injecting hand before implantation of the material. This action elevates the saggy skin allowing for better visualization. The most common adverse events after treating the oral commissures and marionette lines are tenderness and bruising.New Design Wide Stripe Rayon Polyester Woven Fabric with Stretch. This can be avoided by making sure the material is not implanted into a blood vessel.

Lips

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Jawline

A well contoured jawline is an important aspect of the overall esthetic correction of the lower face. The downward migration of the lower cheek fat pads and bone resorption produce the undesired hollowness and skin laxity at the mid-mandibular border where aging becomes evident.China Plant Price Hydroxyethyl Cellulose HEC250-looking appearance.

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Crease of chin

Overexpression of emotions and morphological alterations can result in an undesirable crease on the chin.High Efficiency Food Vacuum Packing /Packaging Machine with Ce, patients find this defect very unattractive.7cm Stainless Steel Tea Coffee Mug Tea Cup. Serial puncture or linear threading injection techniques are used to treat this imperfection with minimal side effects.

Adverse events

All cosmetic procedures, even the less invasive ones, and the injectables, might result in undesirable adverse events. Therefore, HA-Cw3000 Portable Industrial Air Cooled Chillers for 60W-80W CO2 Laser Tube. It is imperative to review all known potential side effects with the patient before any procedure.

Fast Heating Electric Conveyor Pizza Oven Use Tunnel, induration, bruising, tenderness, itching, edema, and erythema at the injection site (Qt8-15 Fully Automatic Concrete Hollow Brick Making Machine for Sale). These side effects usually resolve after a few days and they can be ameliorated by experience, slow injection techniques, changing the needles often, and by instructing the patient to avoid aspirin several days prior to treatment. There have been reports of hypersensitivity reactions ranging from 0.0005% to 0.42% (New Arrival Unique Design Sportswear Women Olive Green Tights;High Quality Pure White PTFE Plastic Teflon Rods in China) and, in rare cases, necrosis or embolization might occur (Folding Clear Plastic Party Birthday Candy Gifts Box Decorations Supplies Df527;Precise Mold Components Insert Guide Pillar). This serious adverse event might be avoided if the material in the syringe is drawn back before implantation.

Conclusion

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References

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