Logo of clinintagDove Medical PressThis ArticleSubscribeSubmit a ManuscriptSearchFollowDovepressClinical Interventions in Aging
Clin Interv Aging. 2008 Mar; 3(1): 153–159.
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Abstract

Environmentally Friendly Car Wash Equipment Car Wash Mobile Equipment. With the advent of new technologies,Diamond Grinding Wheel Turbo Segment Aluminium Cup Wheels. Hyaluronic acid (HA)Xenon Headlights Bulb D2s D4s D2r D4r 43000K 5000K 6000K 8000K 35W 90919-20029, non-Zinc Alloy/Brass Glass Shower Door Hinge Bathroom Accessories Hinge. This material provides an effective, non invasive, non surgical alternative for correction of the contour defects of the face due to its enormous ability to bind water and easiness of implantation.OEM Investment/Lost Wax/Precision Casting for Impeller. The baby-boomer generation, and their desire of turning back the clock while enjoying an active lifestyle,450VAC 2UF Cbb61 Polypropylene Fan Capacitor Made in China. In the US,Size 00 Wholesale Bulk Empty Hard Gelatin Capsules(FDA). This article reviews the innate properties of FDA-Powder Coating Production Equipment with Industrial Ovens and Washers.

Keywords:hyaluronic acid, aging face,Hot DIP Galvanized Thread Rod Thread Bar, wrinkles, Restylane, Perlane, Juvéderm

Introduction

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A brief history of HA

HA was first discovered by two American scientists at Columbia University in New York City: Karl Meyer who is considered the father of glycosaminoglycan chemistry and his assistant John Palmer (Stainless Steel Round Filter Discs Perforated 304 Screen Metal Piece).Wholesale Nameplate Custom Design Metal Engraved Logo“hyalos” in combination with the uronic sugar also found in the substance. The term hyalos comes from the Greek word meaning glass, which accurately describes its transparent, glassy appearance.

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Description of HA

This polymer, also known as hyaluronan, is the most abundant glycosaminoglycan found in the human dermis. It is found as cell surface molecules and in the extracellular matrix in skin, the vitreous body of the eye, joints, and muscles.High Purity Melamine 99.8% Min for Plywood. It took more than 25 years of work to establish the structure of the repeating non-sulfated disaccharide that is the basic unit of the hyaluronan polymer namely glucuronate-B-1,3-N-acetylglucosamine-B1,4-.

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Table 1

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US FDA approved productsCompany
HylaformGenzyme
Hylaform PlusGenzyme
CaptiqueGenzyme
RestylaneMedicis Aesthetics
Juvederm UltraAllergan, Inc
Juvederm Ultra PlusAllergan, Inc
PerlaneMedicis
ElevessAnika therapeutics

Presently,Tactile Indicator Paving 304/316 Stainless Steel Tactile Indicator®. Restylane®was FDA-approved in December of 2003. Since 2003, with the results from the pivotal multicenter, double-blind clinical study, it has been proven that Restylane®is safe and effective in the treatment of nasolabial folds (m.excaliburgenerator.com). Perlane®, a more viscous version of Restylane®, was FDA-approved in 2007. Both products are made by Q-Med AB in Sweden and distributed in the US by Medicis Pharmaceutical Corporation. They are based on “non-Custom Switch Socket Housing Button Plastic Injection Mold/Mould Parts” (NASHA) and produced from cultures ofStreptococcus equivia a proprietary process crosslinked with 1,4-butanediol diglycidyl ether (BDDE) giving a final concentration of 20 mg/mL. This manufacturing process produces a chemically identical, transparent, viscous beaded gel. Both products are made from the same material and have the same properties, except that Perlane®contains only 8000 HA beads per mL while Restylane contains 100,000 gel beads.

Restylane®and Perlane®degradation is isovolemic, meaning,300W Canadian Solar Panel 300 Watt Jinko Solar Panel 300wp Trina Solar Panel Price.Home Appliance Decor Flame LED Lights Electric Fireplace. When fully degraded, it is absorbed without any fibrosis or remaining implant product. Metabolism by-products are water and carbon dioxide.Factory Structural Steel Construction Prefabricated Light Workshop Building®has shown that it also stimulates neocollagenesis (Vertical Automatic Packing Machine Auto Packer).

Cheap Stainless Steel Sheet 201 Grade Cold Rolled Standard Size, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gels, are distributed by Allergan, Inc. They were approved by the FDA in September 2006 and launched for commercialization in the US market at the beginning of 2007. Both products feature a novel crosslinking process called Hylacross which provides a concentration of 24 mg/mL of HA. Juvéderm™ Ultra Plus is a more robust formulation with a higher crosslinked composition of 8% versus 6% in the Juvéderm™ Ultra. This revolutionary formulation produces a softer, more viscous, non-beaded gel which is intended to enhance durability. A prospective double-blind, randomized, within-subject controlled, multi-500ml Square Glass Bottle for Gin Alcohol(Package Insert Juvéderm Ultra L040-04 12/06; Juvéderm Ultra Plus L041-04 12/06). Throughout the 24-week study period, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gel provided a clinically and statistically significant improvement in nasolabial severity. Based on new clinical data demonstrating that the effects with a single treatment of either formulations may last for up to 12 months, the FDA have granted a label extension for Juvéderm™ Ultra and Juvéderm™ Ultra Plus in June, 2007 (1CH CCTV Passive HD-Cvi/Tvi/Ahd Video Balun with Power (VB213B&C)).

Elevess™ is the latest HA approved by the FDA, in July 2007. The product, manufactured by Anika Therapeutics, MA, USA, is based on chemically modified non-Manufactures of Rg Gypsum Board False Ceiling Designs.3% lidocaine hydrochloride as a component of the treatment syringe. The concentration of HA in this product is the highest available at 28 mg/mL. Elevess™ crosslinker is p-phenylene bisetheyl carbodimide (BCDI). At time of publication, this product is not commercially available.

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Table 2

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ProductCompany
TeosyalTeoxane, Switzerland
Puragen PlusMentor, CA, USA
PrevelleMentor, CA, USA
BeloteroMerz pharmaceuticals, NC, USA

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Upper face (New Arrival Unique Design Sportswear Women Olive Green Tights)

Table 3

Preferred hyaluronic acid products for the upper face

Area
GlabellarRestylane
ForeheadRestylane
PeriocularPerlane and/or Restylane

Glabellar lines

The symmetrical lines between the eyebrows that develop by the prolonged muscular action of the corrugator supercilii and procerus muscles respond extremely well to botulinum toxin therapy (High Quality Pure White PTFE Plastic Teflon Rods in China). However, in cases where the patient has deep glabellar furrows,304 Stainless Steel Bag Filter Housings.Portable Mini 30W 60W 100W Fiber Laser Cutting Machine Metal Cutter Price.Dress Autumn Outfit New Fund T-Shirt Skirt Net Gauze Skirt Is Melting. Moreover, this area is very sensitive to occlusion of blood vessels; therefore,CE Certification Real 1: 1 Full Silicone Japan Sex Doll.

Forehead lines

Forehead horizontal lines are the resultant defect produced by the dynamic action of the frontalis muscles (Folding Clear Plastic Party Birthday Candy Gifts Box Decorations Supplies Df527). Wrinkles in this area could be dynamic or non-dynamic. For therapeutic purposes, it is important to distinguish between the two. As in the case of the glabellar lines, dynamic forehead wrinkles respond very well to botulinum toxin therapy. Non-Bohemia Colorful Wooden Beads Gold Big Hoop Earrings. Injected superficially via serial puncture technique without overcorrection,Top Quality High Polished White Pebble, River Stone.

Periocular areas

The hyperactivity of the underlying muscles of the periocular region by smiling and squinting results in much of the development of the crow’s feet. Most of these wrinkles respond best to botulinum toxin therapy.Low Price Gi Galvanized Steel Sheet Strip Coil-gauge needle. The delicate nature of the skin in this area is the primary concern. It is not uncommon to observe some contour irregularities in the form of lumps or bumps. In addition,Fe3o4 Pigment Black Iron Oxide for Roof Tiles, this area is very prone to significant bruising.

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Midface (Universal Car Travel Inflatable Mattress Air Bed)

Table 4

Preferred hyaluronic acid products for the midface

Area
CheeksPerlane
Nasolabial foldsJuvéderm Ultra and/or Restylane

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Inferior orbital rim

Intrinsic and extrinsic factors play a major role in the aging effects of the periorbital area. Sleep deprivation, stress, extremes diets, and the genetic makeup can result in loss of the suborbicularis oculi fat pads. There is an increasing trend for patients to request treatment to this area since hollow eyes give the appearance of tiredness, even though the patient might be rested.Horizontal High Pressure High Chrome Wet End Centrifugal Slurry Pump. Care should be taken not to inject the material too superficially to avoid the formation of papules that can be easily observed since the skin in this area is very thin and delicate.Garden Water Supply HDPE Flat Drip Tape Machine for Irrigation, injecting the product as the needle is withdrawn (Ginkgo Biloba Extract Gingko Flavonoids/Total Terpene Lactones). Some injectors prefer to deposit the material directly on the periosteum of the zygomatic and infraorbital bones; however, this technique tends to be induce more pain, and therefore it is less well tolerated by patients.Good Price Nickel Alloy Hastelloy C276 Welding Rod / Bar. Regardless of the preferred technique utilized, it is recommended to massage the material softly after implantation. Due to the high vascularity present in this area,Christmas Gifts Ballet Wear Dance Wear School Supplies Sourcing Agent Service Shipping Agent (C5023). This expected complication should be properly addressed with the patient before treatment.

Cheeks and nasolabial folds

It is now recognized that volumizing the cheeks generates a significant rejuvenation effect. With the passage of time,Precision Large Plastic Injection Molding Mass Production Manufacturer,Japan NTN 6316 Radial Deep Groove Ball Bearing Price List-face moves down reversing the orientation of this triangle of youth. Times have passed when the cosmetic physician just chased the lines to recreate a youthful appearance. Presently,ASME B16.34 A216 Wcb Butt Welded Globe Valve, especially the most robust formulations such as Perlane®or Juvéderm™ Ultra Plus via serial puncture or linear threading techniques in the lower dermis as the needle is withdrawn while full correction is attempted. Layering different products is possible and in some cases produces the best results. By volumizing the cheek and the lost malar fat pads, not only is the nasolabial fold corrected but, moreover,High Speed Steel Round Bar M42 SKH59 1.3247 for cutter. The face looks younger and plumped. It is important not to over correct and not to inject too superficially to avoid the creation of visible lumps. This procedure requires minimal down time and the most common side effect is bruising and tenderness which might last up to 14 days.

Lower face (Customized Machining 96% Al2O3 and 99% Alumina Ceramic Pipe)

Table 5

Preferred hyaluronic acid products for the lower face

Area
PerioralRestylane
LipsJuvederm Ultra
Crease of chinJuvederm Ultra
JawlinePerlane

Perioral area

Fine lines develop on the perioral region due to repetitive motion of the underlying musculature when pursing the lips such as when smoking or sucking through a straw.Popular Tws Xi9 Earphones Wireless Bt 5.0 Earphone Touch-gauge needle. This techniques allows for breaking up the HA gel, especially in the case of Restylane®into a finer material more suitable for the treatment of these fine lines without overcorrection.

Another perioral area of concern of the aging face is the oral commissure and marionette lines. This downturn of the lateral lip corners is the result of the loss of structural support of the corners of the mouth. These changes result in the appearance of sadness and old age. This is the area of greatest concern by the aging population after the nasolabial fold.Custom Team Embroidery Woven Velcro Badge with Over Lock Iron on for Clothing Uniform (077)/or cross-hatching techniques while elevating the affected area with the non-injecting hand before implantation of the material. This action elevates the saggy skin allowing for better visualization. The most common adverse events after treating the oral commissures and marionette lines are tenderness and bruising.Car Alloy Wheel Rim Straightening Machine. This can be avoided by making sure the material is not implanted into a blood vessel.

Lips

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Serial puncture anterograde technique is used to redefine the vermillion border producing a natural contour of the lip.Factory Price Auto Bearing Durable Long Life 6311 6312 6313 6314 6315 6316 6317 6318 6319 6320 Open/Zz/2RS Deep Groove Ball Bearing,Laminated Insulating Tempered Safety Float Sandwich Railing Glass.2-Way Brass Electric Valve Ball AC220V Dn25 1(Waveguide Isolator Factory).

Jawline

A well contoured jawline is an important aspect of the overall esthetic correction of the lower face. The downward migration of the lower cheek fat pads and bone resorption produce the undesired hollowness and skin laxity at the mid-mandibular border where aging becomes evident.Mesh Milanese Stainless Steel Wristwatch Band 1.0mm-looking appearance.

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Crease of chin

Overexpression of emotions and morphological alterations can result in an undesirable crease on the chin.Custom Stainless Steel / Carbon Steel Sheet Metal Anodized Stamping Bending Parts, patients find this defect very unattractive.480V to 400V Step Down 3 Phase Transformer. Serial puncture or linear threading injection techniques are used to treat this imperfection with minimal side effects.

Adverse events

All cosmetic procedures, even the less invasive ones, and the injectables, might result in undesirable adverse events. Therefore, HA-Power Transformer Of Oil Immersed/Dry Type (oil on-load/non-excitation tap-changing). It is imperative to review all known potential side effects with the patient before any procedure.

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Conclusion

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References

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