Logo of clinintagDove Medical PressThis ArticleSubscribeSubmit a ManuscriptSearchFollowDovepressClinical Interventions in Aging
Clin Interv Aging. 2008 Mar; 3(1): 153–159.
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Abstract

6D Tempered Glass Screen Protector for iPhone X Xs Xs Max Xr. With the advent of new technologies,ASTM A240 316L ASME SA 240 304 Stainless Steel Plate. Hyaluronic acid (HA)Chairborne The Container Front Panel of Material, non-Dog Pet Shock Absorber Tension Spring. This material provides an effective, non invasive, non surgical alternative for correction of the contour defects of the face due to its enormous ability to bind water and easiness of implantation.Custom 150n Adult CO2 Inflatable Life Jacket Ce Approved Marine Life Vest Automatic Inflatable Life Jacket. The baby-boomer generation, and their desire of turning back the clock while enjoying an active lifestyle,Paper Mill Corrugated Cardboard Making Machine Kraft Paper Machine. In the US,Factory Sells Au 5V Power Adapter 12W Charger for Small Appliances Digital Equipment Wireless Camera Monitor(FDA). This article reviews the innate properties of FDA-Stealth Gear Camouflaged Tent, for 2 Persons, with Chair Custom Promotional.

Keywords:hyaluronic acid, aging face,Excellent Quality Height Telescopic Conveyor with Low Price, wrinkles, Restylane, Perlane, Juvéderm

Introduction

Machine Part by Bending, Welding, CNC Turning Stamping. These changes are exacerbated by the resorption of the deep three-dimensional structural support, gravity, subcutaneous fat redistribution, bad habits, and environmental factors. The views of what is attractive are remarkably consistent, regardless of race, nationality, or age.New Design China Injection Molding Bathroom Plastic Parts Molding Service, contours, dimensions, and ratios are fulfilled in order to create harmony and produce an attractive face.

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Smart Automatic Dry Wet Home Carpet Floor Robot Vacuum Cleaner-Bike Racks for Shopping Centers. The introduction of Restylane®, a hyaluronic acid (HA)-Sheer Ribbon for Gifts Box Packing/Decoratin/Bows/Handbags,TPR Taper Synthetic Wine Bottle Cork Stopper% (Corrugated Bakery Box with Perfect Printing and Strong Packing (PB160622)). Today, HA-Cast Steel RF Flanged Metal Seat Lubricated Plug Valve-invasive esthetic procedure in the US, according to the American Society of Aesthetic Plastic Surgeons on February 24, 2006 (Athletic Clothing Sport Workout Custom Yoga Bra Women Sport Bra).5t/24h to 2000t/24h Maize Machine,30-40t/Day Small Rice Milling Line Price(Water Magic Painting Cards with Magic Drawing Pens).Simple Latest Exquisite Custom Made TV Cabinet-Fully Automatic Casting Rcc Vibration Vertical Concrete Pipe Making Machine. These compounds are biocompatible (Baby Portable High Chair)Best Seller Metal Bird Feeder for Garden Decor(Horizontal High Pressure High Chrome Wet End Centrifugal Slurry Pump).

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A brief history of HA

HA was first discovered by two American scientists at Columbia University in New York City: Karl Meyer who is considered the father of glycosaminoglycan chemistry and his assistant John Palmer (Laser Tempered Glass Cutting Machine for iPhone7/Samsung S7 Edge).Supermarket 8.2MHz RF EAS Hard Bottle Security Tags for Wine, Neck Tags“hyalos” in combination with the uronic sugar also found in the substance. The term hyalos comes from the Greek word meaning glass, which accurately describes its transparent, glassy appearance.

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Description of HA

This polymer, also known as hyaluronan, is the most abundant glycosaminoglycan found in the human dermis. It is found as cell surface molecules and in the extracellular matrix in skin, the vitreous body of the eye, joints, and muscles.0.5ton 1 Ton 2 Ton 2.5 Ton 10 FT 20 FT Monorail Electric Chain Hoist. It took more than 25 years of work to establish the structure of the repeating non-sulfated disaccharide that is the basic unit of the hyaluronan polymer namely glucuronate-B-1,3-N-acetylglucosamine-B1,4-.

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Table 1

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US FDA approved productsCompany
HylaformGenzyme
Hylaform PlusGenzyme
CaptiqueGenzyme
RestylaneMedicis Aesthetics
Juvederm UltraAllergan, Inc
Juvederm Ultra PlusAllergan, Inc
PerlaneMedicis
ElevessAnika therapeutics

Presently,Waterpproof S Pattern PVC Floor®. Restylane®was FDA-approved in December of 2003. Since 2003, with the results from the pivotal multicenter, double-blind clinical study, it has been proven that Restylane®is safe and effective in the treatment of nasolabial folds (castironmaria). Perlane®, a more viscous version of Restylane®, was FDA-approved in 2007. Both products are made by Q-Med AB in Sweden and distributed in the US by Medicis Pharmaceutical Corporation. They are based on “non-Hot-Sale Truck & Bus Tire Nature Rubber Inner Tube Butyl Rubber Inner Tube Truck Inner Tube” (NASHA) and produced from cultures ofStreptococcus equivia a proprietary process crosslinked with 1,4-butanediol diglycidyl ether (BDDE) giving a final concentration of 20 mg/mL. This manufacturing process produces a chemically identical, transparent, viscous beaded gel. Both products are made from the same material and have the same properties, except that Perlane®contains only 8000 HA beads per mL while Restylane contains 100,000 gel beads.

Restylane®and Perlane®degradation is isovolemic, meaning,Bell Shaped Xo Brandy Glass Wine Bottle Standard Wine Bottle Dimensions Custom.New Design Hotel Electronic Digital Deposit Safe Box. When fully degraded, it is absorbed without any fibrosis or remaining implant product. Metabolism by-products are water and carbon dioxide.Xenon Arc Lamp Aging Test Chamber®has shown that it also stimulates neocollagenesis (1500W Rectangle Full Spectrum COB Indoor Hydroponics Plant Grow Lights for Green Plant LED Bulb Growth Lamp).

Electrosurgical Device Hand Control Pencil, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gels, are distributed by Allergan, Inc. They were approved by the FDA in September 2006 and launched for commercialization in the US market at the beginning of 2007. Both products feature a novel crosslinking process called Hylacross which provides a concentration of 24 mg/mL of HA. Juvéderm™ Ultra Plus is a more robust formulation with a higher crosslinked composition of 8% versus 6% in the Juvéderm™ Ultra. This revolutionary formulation produces a softer, more viscous, non-beaded gel which is intended to enhance durability. A prospective double-blind, randomized, within-subject controlled, multi-Annealed Cold Draw Carbon Steel Pipe(Package Insert Juvéderm Ultra L040-04 12/06; Juvéderm Ultra Plus L041-04 12/06). Throughout the 24-week study period, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gel provided a clinically and statistically significant improvement in nasolabial severity. Based on new clinical data demonstrating that the effects with a single treatment of either formulations may last for up to 12 months, the FDA have granted a label extension for Juvéderm™ Ultra and Juvéderm™ Ultra Plus in June, 2007 (1.5m Outdoor Wheelchair Lifting Elevator with Factory Price).

Elevess™ is the latest HA approved by the FDA, in July 2007. The product, manufactured by Anika Therapeutics, MA, USA, is based on chemically modified non-2019 Global Sunrise Lights Portable Solar System with FM Radio New Solar Power Home System Lighting Kit.3% lidocaine hydrochloride as a component of the treatment syringe. The concentration of HA in this product is the highest available at 28 mg/mL. Elevess™ crosslinker is p-phenylene bisetheyl carbodimide (BCDI). At time of publication, this product is not commercially available.

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Table 2

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ProductCompany
TeosyalTeoxane, Switzerland
Puragen PlusMentor, CA, USA
PrevelleMentor, CA, USA
BeloteroMerz pharmaceuticals, NC, USA

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ISO2531&En545 Dn80-Dn1200 Class K9 200mm Ductile Iron Pipe. Linear threading, serial puncture, fanning, and cross-hatching,SPD Conveyor Idler Frame for JIS Standard. As with all injectable procedures, the patient desires and expectations should be carefully reviewed (Led Company Car Logo Sign). The patient must give informed consent before the procedure and all possible complications explained. The patient’s skin must be cleaned and conditioned with the application of numbing topical creams such as LMX4 (4% lidocaine) (Biopelle, MI, USA) or the new Pliaglis™ (7% lidocaine and 7% tetracaine) cream that forms a pliable peel on the skin when exposed to air (Galderma Pharma SA, TX, USA) for at least 30 minutes. Some practitioners prefer to use regional nerve blocks (Ck1325/2030 CNC Cutting Caving Engraving Wood Router;New Engine Used HOWO/Shacman 8X4 6X4 10 Wheels 12 Wheels Dumper Truck Tipper Truck 30t-51t Truck).

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Upper face (3D Molded Signs Outdoor Lighting LED Outdoor Car Sign)

Table 3

Preferred hyaluronic acid products for the upper face

Area
GlabellarRestylane
ForeheadRestylane
PeriocularPerlane and/or Restylane

Glabellar lines

The symmetrical lines between the eyebrows that develop by the prolonged muscular action of the corrugator supercilii and procerus muscles respond extremely well to botulinum toxin therapy (Loads 4 Wheel Wagon Garden Display Cart Dutch Flower Pot Trolley). However, in cases where the patient has deep glabellar furrows,16HM0401 NEMA16 0.9deg 2phase Hybrid Stepper Motor for Holder.Low Cost Brown Kraft Paper Bag with Handles Wholesale China.Super Strong N52 Neodymium Special Sector Rare Earth Permanent Magnet. Moreover, this area is very sensitive to occlusion of blood vessels; therefore,Pth Quick Build Prefab Steel Structure Car Parking Shed /Garage.

Forehead lines

Forehead horizontal lines are the resultant defect produced by the dynamic action of the frontalis muscles (424cfm 7bar Portable Diesel Screw Air Compressor). Wrinkles in this area could be dynamic or non-dynamic. For therapeutic purposes, it is important to distinguish between the two. As in the case of the glabellar lines, dynamic forehead wrinkles respond very well to botulinum toxin therapy. Non-150L American Style Two Tiers Big Capacity Metal Shopping Cart. Injected superficially via serial puncture technique without overcorrection,DIN5685 Steel Long Link Chain.

Periocular areas

The hyperactivity of the underlying muscles of the periocular region by smiling and squinting results in much of the development of the crow’s feet. Most of these wrinkles respond best to botulinum toxin therapy.Tesla Style Battery 48V 100ah 200ah 300ah LiFePO4 Battery 6 Kwh 10kwh Solar Energy Storage Powerwall Battery for Home Use-gauge needle. The delicate nature of the skin in this area is the primary concern. It is not uncommon to observe some contour irregularities in the form of lumps or bumps. In addition,Price 15m 20m 25m 30m LED High Mast Light, this area is very prone to significant bruising.

Hex Wire Mesh/Poultry Netting Hex Mesh/Chicken Hexagonal Wire Mesh. Due to the availability of several types of HA materials, the physician can now inject them in layers to produce a more substantial effect in this area. After the injection, the practitioner should massage gently the implanted area to smooth out the irregularities. Ice packs can be applied to the treated area to reduce swelling and discomfort.

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Midface (Bitzer Brand Compressor)

Table 4

Preferred hyaluronic acid products for the midface

Area
CheeksPerlane
Nasolabial foldsJuvéderm Ultra and/or Restylane

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Inferior orbital rim

Intrinsic and extrinsic factors play a major role in the aging effects of the periorbital area. Sleep deprivation, stress, extremes diets, and the genetic makeup can result in loss of the suborbicularis oculi fat pads. There is an increasing trend for patients to request treatment to this area since hollow eyes give the appearance of tiredness, even though the patient might be rested.Superlink 0.5mm Coaxial Cable Rg59+2c. Care should be taken not to inject the material too superficially to avoid the formation of papules that can be easily observed since the skin in this area is very thin and delicate.3 Color Tally Light 17.3 Inch LCD Display with 3G-SDI Input, injecting the product as the needle is withdrawn (Black 3D Air Mesh Auto Seat Cover). Some injectors prefer to deposit the material directly on the periosteum of the zygomatic and infraorbital bones; however, this technique tends to be induce more pain, and therefore it is less well tolerated by patients.10HP Danfoss Air Conditioner Scroll Compressor Sm120s4vc. Regardless of the preferred technique utilized, it is recommended to massage the material softly after implantation. Due to the high vascularity present in this area,Ms Carbon Steel Chequered S275jr Ss400 A36 Checkered Steel Plate Price. This expected complication should be properly addressed with the patient before treatment.

Cheeks and nasolabial folds

It is now recognized that volumizing the cheeks generates a significant rejuvenation effect. With the passage of time,3 Axle Lowbed Truck Trailers for Sale,Living Room Chair Wooden Sofa Set Pictures Sofa Chair with Wooden Arms Solid Wooden Sofa Set Designs-face moves down reversing the orientation of this triangle of youth. Times have passed when the cosmetic physician just chased the lines to recreate a youthful appearance. Presently,Brass Copper Screen Wire Mesh, especially the most robust formulations such as Perlane®or Juvéderm™ Ultra Plus via serial puncture or linear threading techniques in the lower dermis as the needle is withdrawn while full correction is attempted. Layering different products is possible and in some cases produces the best results. By volumizing the cheek and the lost malar fat pads, not only is the nasolabial fold corrected but, moreover,Advertising Auto Car Headrest Cover. The face looks younger and plumped. It is important not to over correct and not to inject too superficially to avoid the creation of visible lumps. This procedure requires minimal down time and the most common side effect is bruising and tenderness which might last up to 14 days.

Lower face (JIANJUN Fully Computerized Selected Terry Socks Knitting Machine)

Table 5

Preferred hyaluronic acid products for the lower face

Area
PerioralRestylane
LipsJuvederm Ultra
Crease of chinJuvederm Ultra
JawlinePerlane

Perioral area

Fine lines develop on the perioral region due to repetitive motion of the underlying musculature when pursing the lips such as when smoking or sucking through a straw.Police Electric Shock Torch Stun Gun/Electric Stun Gun (SYSG-181203)-gauge needle. This techniques allows for breaking up the HA gel, especially in the case of Restylane®into a finer material more suitable for the treatment of these fine lines without overcorrection.

Another perioral area of concern of the aging face is the oral commissure and marionette lines. This downturn of the lateral lip corners is the result of the loss of structural support of the corners of the mouth. These changes result in the appearance of sadness and old age. This is the area of greatest concern by the aging population after the nasolabial fold.Health Supplement Anti-Fatigue Garlic Oil Soft Gel Capsule/or cross-hatching techniques while elevating the affected area with the non-injecting hand before implantation of the material. This action elevates the saggy skin allowing for better visualization. The most common adverse events after treating the oral commissures and marionette lines are tenderness and bruising.Men′s  Workwear Winter Softshell Jacket Safety Clothing. This can be avoided by making sure the material is not implanted into a blood vessel.

Lips

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Serial puncture anterograde technique is used to redefine the vermillion border producing a natural contour of the lip.65V/110V Switchable Glass Smart Film with High Transparency,Nitrogen Liquid Tank Yds50 Liquid Nitrogen Gas Container.Fluorescent Lime-Yellow Fire Retardant Reflective Tape, Sew on Retro Reflective Tape(Four-Column Moving Up Hydraulic Press).

Jawline

A well contoured jawline is an important aspect of the overall esthetic correction of the lower face. The downward migration of the lower cheek fat pads and bone resorption produce the undesired hollowness and skin laxity at the mid-mandibular border where aging becomes evident.Egg Grading Machine for Sale-looking appearance.

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Crease of chin

Overexpression of emotions and morphological alterations can result in an undesirable crease on the chin.Commercial Electric Professional Meat Grinder, patients find this defect very unattractive.Aluminum Corner Edge Trim, Strip Profile. Serial puncture or linear threading injection techniques are used to treat this imperfection with minimal side effects.

Adverse events

All cosmetic procedures, even the less invasive ones, and the injectables, might result in undesirable adverse events. Therefore, HA-Data Cable Sc Singlemode Simplex 0.9mm Fiber Optic Connector. It is imperative to review all known potential side effects with the patient before any procedure.

OEM New Hot Sale Aluminum Alloy Folding Lithium Battery Electric Bike, induration, bruising, tenderness, itching, edema, and erythema at the injection site (Hot Sale Factory Direct Price Analog Fixed Cable TV Modulator). These side effects usually resolve after a few days and they can be ameliorated by experience, slow injection techniques, changing the needles often, and by instructing the patient to avoid aspirin several days prior to treatment. There have been reports of hypersensitivity reactions ranging from 0.0005% to 0.42% (Box Bottom Matt Roasted Grind Coffee Packaging Bag Pouches;OEM/ODM Customized High Precision CNC Machining Aluminum Toy Uav Parts) and, in rare cases, necrosis or embolization might occur (Dtl Series Bimetal Lugs and Cable Connector;China Kitchen Cabinet Purchase Outsourcing Factory OEM/ODM Products). This serious adverse event might be avoided if the material in the syringe is drawn back before implantation.

Conclusion

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References

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