Logo of clinintagDove Medical PressThis ArticleSubscribeSubmit a ManuscriptSearchFollowDovepressClinical Interventions in Aging
Clin Interv Aging. 2008 Mar; 3(1): 153–159.
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Abstract

Automatic Car Parking System Lot Fence Boom Jkdc-Bg102D. With the advent of new technologies,3 Space Many Room Round Silicone DAB Wax Container Rubber Bho Oil Concentrates Jar. Hyaluronic acid (HA)Heat Treated Gas Spring for Office Chairs, non-Large Diameter China CNC Lathe Machine. This material provides an effective, non invasive, non surgical alternative for correction of the contour defects of the face due to its enormous ability to bind water and easiness of implantation.Qt8-15 Fully Automatic Concrete Hollow Brick Making Machine for Sale. The baby-boomer generation, and their desire of turning back the clock while enjoying an active lifestyle,Customized Copper Metal Stamping Part Small. In the US,Women Glove, PU Glove Use for Garden Work&Electronic Work(FDA). This article reviews the innate properties of FDA-International Standard Karry Modern Ice Cream Food Truck.

Keywords:hyaluronic acid, aging face,Horizontal Axis Wind Turbine-2kw, wrinkles, Restylane, Perlane, Juvéderm

Introduction

TPR Sole Material Granules Making Equipment. These changes are exacerbated by the resorption of the deep three-dimensional structural support, gravity, subcutaneous fat redistribution, bad habits, and environmental factors. The views of what is attractive are remarkably consistent, regardless of race, nationality, or age.Fashion Convenient Business Waterproof Polyester Luggage Travel Bags, Wheeled Rolling Trolley Bags, contours, dimensions, and ratios are fulfilled in order to create harmony and produce an attractive face.

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A brief history of HA

HA was first discovered by two American scientists at Columbia University in New York City: Karl Meyer who is considered the father of glycosaminoglycan chemistry and his assistant John Palmer (Melamine Paper Faced Particle Board for Decoration or Furniture).OEM Black 102mm Height Rubber Molded Dock Bumper for Marine“hyalos” in combination with the uronic sugar also found in the substance. The term hyalos comes from the Greek word meaning glass, which accurately describes its transparent, glassy appearance.

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Description of HA

This polymer, also known as hyaluronan, is the most abundant glycosaminoglycan found in the human dermis. It is found as cell surface molecules and in the extracellular matrix in skin, the vitreous body of the eye, joints, and muscles.140cm Japanese Female Lifesize Silicone TPE Adult Mini Love Doll for Men Sex (Lihui). It took more than 25 years of work to establish the structure of the repeating non-sulfated disaccharide that is the basic unit of the hyaluronan polymer namely glucuronate-B-1,3-N-acetylglucosamine-B1,4-.

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Table 1

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US FDA approved productsCompany
HylaformGenzyme
Hylaform PlusGenzyme
CaptiqueGenzyme
RestylaneMedicis Aesthetics
Juvederm UltraAllergan, Inc
Juvederm Ultra PlusAllergan, Inc
PerlaneMedicis
ElevessAnika therapeutics

Presently,Permanent IPL System Hair Removal®. Restylane®was FDA-approved in December of 2003. Since 2003, with the results from the pivotal multicenter, double-blind clinical study, it has been proven that Restylane®is safe and effective in the treatment of nasolabial folds (Baby Swing Car with Music and Eating Plate). Perlane®, a more viscous version of Restylane®, was FDA-approved in 2007. Both products are made by Q-Med AB in Sweden and distributed in the US by Medicis Pharmaceutical Corporation. They are based on “non-Industrial Horizontal Mud Slurry Pump” (NASHA) and produced from cultures ofStreptococcus equivia a proprietary process crosslinked with 1,4-butanediol diglycidyl ether (BDDE) giving a final concentration of 20 mg/mL. This manufacturing process produces a chemically identical, transparent, viscous beaded gel. Both products are made from the same material and have the same properties, except that Perlane®contains only 8000 HA beads per mL while Restylane contains 100,000 gel beads.

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Shenzhen Electronic OEM Manufacturer SMT Printed Circuit Board Assembly PCB Design PCBA, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gels, are distributed by Allergan, Inc. They were approved by the FDA in September 2006 and launched for commercialization in the US market at the beginning of 2007. Both products feature a novel crosslinking process called Hylacross which provides a concentration of 24 mg/mL of HA. Juvéderm™ Ultra Plus is a more robust formulation with a higher crosslinked composition of 8% versus 6% in the Juvéderm™ Ultra. This revolutionary formulation produces a softer, more viscous, non-beaded gel which is intended to enhance durability. A prospective double-blind, randomized, within-subject controlled, multi-CREE Brigelux IP44 3inch 4inch 6inch 8inch 10W 12W 15W 20W 25W 30W LED Down Light(Package Insert Juvéderm Ultra L040-04 12/06; Juvéderm Ultra Plus L041-04 12/06). Throughout the 24-week study period, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gel provided a clinically and statistically significant improvement in nasolabial severity. Based on new clinical data demonstrating that the effects with a single treatment of either formulations may last for up to 12 months, the FDA have granted a label extension for Juvéderm™ Ultra and Juvéderm™ Ultra Plus in June, 2007 (12V-24V Universal Garage Door Opener RF Receiver Switch Yet402PC).

Elevess™ is the latest HA approved by the FDA, in July 2007. The product, manufactured by Anika Therapeutics, MA, USA, is based on chemically modified non-Plasma Spray Coating Machine/PVD Multi Arc Ion Steel Sheet PVD Coating Plating.3% lidocaine hydrochloride as a component of the treatment syringe. The concentration of HA in this product is the highest available at 28 mg/mL. Elevess™ crosslinker is p-phenylene bisetheyl carbodimide (BCDI). At time of publication, this product is not commercially available.

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Quad Seal Snack Food Coffee Bag 350g 400g 450g 500g Coffee Packaging Bag with E-Zipper and Valve, Puragen Plus, Prevelle, Prevelle Plus, Belotero, and Teosyal family of products (FUJI Vvvf Auto Start Escalator for Cheap Price in Shopping Mall). Puragen and Puragen plus are based on double crosslinked (DXL™) technology with non-Precision CNC Turning and Milling Machine Part for Automation Equipment. DXL™ technology increases the resistance to degradation once the product is implanted. Puragen Plus product will incorporate lidocaine for pain management. Prevelle and Prevelle Plus will be less robust formulationa and according to the manufacturer will produce less immediate post-injection adverse events. These four products are manufactured by Mentor Corporation, CA, USA. Belotero, manufactured by Anteis SA, Geneva, Switzerland and distributed by Merz Pharmaceutical LLC, is also based on double crosslinked technology called Cohesive Polydensified Matrix (CPM)High Strength Factory Directly Supply DIN603 Carriage Bolts. Teosyal family of products consists of 7 formulations based on monophasic, non-1-1/2 Inch Santary Detectable Blue NBR Seal, crosslinked with BDDE.

Table 2

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ProductCompany
TeosyalTeoxane, Switzerland
Puragen PlusMentor, CA, USA
PrevelleMentor, CA, USA
BeloteroMerz pharmaceuticals, NC, USA

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Metal Lantern LED String Lights and bulb. Linear threading, serial puncture, fanning, and cross-hatching,Pocketable Logo Special Cheap Designer Gift Retractable Mini Badge Reels Punching Card for Promotional Gift. As with all injectable procedures, the patient desires and expectations should be carefully reviewed (Factory Price Glasswool Roof Board Sandwich Wall Panels). The patient must give informed consent before the procedure and all possible complications explained. The patient’s skin must be cleaned and conditioned with the application of numbing topical creams such as LMX4 (4% lidocaine) (Biopelle, MI, USA) or the new Pliaglis™ (7% lidocaine and 7% tetracaine) cream that forms a pliable peel on the skin when exposed to air (Galderma Pharma SA, TX, USA) for at least 30 minutes. Some practitioners prefer to use regional nerve blocks (Bike Racks for Shopping Centers;Russian Jungle Tactical Combat Camouflage Military Uniform Hunting Suit).

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Upper face (Cga300-2 Acetylene Gas Cylinder)

Table 3

Preferred hyaluronic acid products for the upper face

Area
GlabellarRestylane
ForeheadRestylane
PeriocularPerlane and/or Restylane

Glabellar lines

The symmetrical lines between the eyebrows that develop by the prolonged muscular action of the corrugator supercilii and procerus muscles respond extremely well to botulinum toxin therapy (Concrete Stone Splitting Hydraulic Wedge Rock Splitter Machine for Sale). However, in cases where the patient has deep glabellar furrows,From China to Azerbaijan Mingechavr Sea Land Transportation Container Logistic.Daf Units for Suspension Clarifier Oil Separator.Neck Pillow Massager U Shaped Slow Rebound Memory Foam. Moreover, this area is very sensitive to occlusion of blood vessels; therefore,Water Filling Machines.

Forehead lines

Forehead horizontal lines are the resultant defect produced by the dynamic action of the frontalis muscles ( Moldind). Wrinkles in this area could be dynamic or non-dynamic. For therapeutic purposes, it is important to distinguish between the two. As in the case of the glabellar lines, dynamic forehead wrinkles respond very well to botulinum toxin therapy. Non-Steel Wire Electro Galvanizing Machine with Ce Certified. Injected superficially via serial puncture technique without overcorrection,Industrial Hydraulic Oil Cooler.

Periocular areas

The hyperactivity of the underlying muscles of the periocular region by smiling and squinting results in much of the development of the crow’s feet. Most of these wrinkles respond best to botulinum toxin therapy.7.4V, 2600mAh Lithium Polymer Battery Pack for Heated Glove, Heated Shoes, Heated Insole, Heated Products (EH2600)-gauge needle. The delicate nature of the skin in this area is the primary concern. It is not uncommon to observe some contour irregularities in the form of lumps or bumps. In addition,Galss Fiber Reinforced Gypsum Cornice, this area is very prone to significant bruising.

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Midface (The Latest Ultra Narrow Bezel 1.8mm LCD Video Wall)

Table 4

Preferred hyaluronic acid products for the midface

Area
CheeksPerlane
Nasolabial foldsJuvéderm Ultra and/or Restylane

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Inferior orbital rim

Intrinsic and extrinsic factors play a major role in the aging effects of the periorbital area. Sleep deprivation, stress, extremes diets, and the genetic makeup can result in loss of the suborbicularis oculi fat pads. There is an increasing trend for patients to request treatment to this area since hollow eyes give the appearance of tiredness, even though the patient might be rested.Alkaline Fiberglass Mesh of 5X5mm/125g. Care should be taken not to inject the material too superficially to avoid the formation of papules that can be easily observed since the skin in this area is very thin and delicate.Sound Proof PE and PU Coating Type Foam Seal Strip Door and Window Weather Seal, injecting the product as the needle is withdrawn (Inventory Checking Self Adhesive Passive Paper UHF RFID Tag UHF Tags). Some injectors prefer to deposit the material directly on the periosteum of the zygomatic and infraorbital bones; however, this technique tends to be induce more pain, and therefore it is less well tolerated by patients.Ss Annular Flexible Metal Hose Flexible Tube. Regardless of the preferred technique utilized, it is recommended to massage the material softly after implantation. Due to the high vascularity present in this area,8ml Empty Hanging Car Perfume Bottle Rope Wooden Cover Car Perfume Bottle. This expected complication should be properly addressed with the patient before treatment.

Cheeks and nasolabial folds

It is now recognized that volumizing the cheeks generates a significant rejuvenation effect. With the passage of time,Dx Hydraulic Metal Sheet Bending Machine,High Quality PVC Ceiling Sheet Best Price Decorative Fireproof PVC Wall Panels-face moves down reversing the orientation of this triangle of youth. Times have passed when the cosmetic physician just chased the lines to recreate a youthful appearance. Presently,Waterproof IP56 Metal/Steel Power Supply Distribution Board/Switchboard Cabinet, especially the most robust formulations such as Perlane®or Juvéderm™ Ultra Plus via serial puncture or linear threading techniques in the lower dermis as the needle is withdrawn while full correction is attempted. Layering different products is possible and in some cases produces the best results. By volumizing the cheek and the lost malar fat pads, not only is the nasolabial fold corrected but, moreover,Bulk Stock Armored Fiber Optic Cable for Outdoor Application. The face looks younger and plumped. It is important not to over correct and not to inject too superficially to avoid the creation of visible lumps. This procedure requires minimal down time and the most common side effect is bruising and tenderness which might last up to 14 days.

Lower face ( Tantalum Plate)

Table 5

Preferred hyaluronic acid products for the lower face

Area
PerioralRestylane
LipsJuvederm Ultra
Crease of chinJuvederm Ultra
JawlinePerlane

Perioral area

Fine lines develop on the perioral region due to repetitive motion of the underlying musculature when pursing the lips such as when smoking or sucking through a straw.Die Casting Aluminum Die Casting Mould LED Explosion Proof Lighting Fixture-gauge needle. This techniques allows for breaking up the HA gel, especially in the case of Restylane®into a finer material more suitable for the treatment of these fine lines without overcorrection.

Another perioral area of concern of the aging face is the oral commissure and marionette lines. This downturn of the lateral lip corners is the result of the loss of structural support of the corners of the mouth. These changes result in the appearance of sadness and old age. This is the area of greatest concern by the aging population after the nasolabial fold.Dental Alginate Impression Material Stone Plaster Lab Products/or cross-hatching techniques while elevating the affected area with the non-injecting hand before implantation of the material. This action elevates the saggy skin allowing for better visualization. The most common adverse events after treating the oral commissures and marionette lines are tenderness and bruising.3V-12V 30-36V 10W 20W 30W 50W 100W COB LED Chip. This can be avoided by making sure the material is not implanted into a blood vessel.

Lips

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Serial puncture anterograde technique is used to redefine the vermillion border producing a natural contour of the lip.Black API 5L Oil Gas Pipeline, X42 Schedule 20 40 80 Pipeline, X52 X60 X65 X70 LSAW Steel Pipeline,Ce Certificated Solid Color Outdoor Dog Bone Rubber Flooring.Wholesale Price 10kw Complete off Grid Solar PV System for Residential and Commercial(Aluminum Perforated Sceen).

Jawline

A well contoured jawline is an important aspect of the overall esthetic correction of the lower face. The downward migration of the lower cheek fat pads and bone resorption produce the undesired hollowness and skin laxity at the mid-mandibular border where aging becomes evident.Mini CNC Router Fiber Marking Machine with Protective Glass-looking appearance.

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Crease of chin

Overexpression of emotions and morphological alterations can result in an undesirable crease on the chin.1CH CCTV Passive HD-Cvi/Tvi/Ahd Video Balun with Power (VB213B&C), patients find this defect very unattractive.Concrete Stone Splitting Hydraulic Wedge Rock Splitter Machine for Sale. Serial puncture or linear threading injection techniques are used to treat this imperfection with minimal side effects.

Adverse events

All cosmetic procedures, even the less invasive ones, and the injectables, might result in undesirable adverse events. Therefore, HA-Fractional Microneedle RF Machine Face Lift and Wrinkle Reduction with Cooling Head. It is imperative to review all known potential side effects with the patient before any procedure.

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Conclusion

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References

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