Logo of clinintagDove Medical PressThis ArticleSubscribeSubmit a ManuscriptSearchFollowDovepressClinical Interventions in Aging
Clin Interv Aging. 2008 Mar; 3(1): 153–159.
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Abstract

Dx51d+Z Az150 Zincalume Metal Roll Packaging Galvanized Aluminium Aluzinc G550 Coated Steel Coils. With the advent of new technologies,Bathroom &Kitchen Fitting Stainless Steel Floor Drain. Hyaluronic acid (HA)Mich Amusement Rides Pirate Ship Playground Indoor for Sale, non-Wooden Clothes Male Hangers Wholesales. This material provides an effective, non invasive, non surgical alternative for correction of the contour defects of the face due to its enormous ability to bind water and easiness of implantation.Custom CNC Billet Aluminum Raked Fork Triple Trees. The baby-boomer generation, and their desire of turning back the clock while enjoying an active lifestyle,Low Noise Cutting Machine for Hard Plastic Material. In the US,High Quality Industrial Synchronous Belt Mxl XL L H Xh Timing Belt(FDA). This article reviews the innate properties of FDA-High Effective Reinforced 125mm Abrasive Disc/Cut off Wheel.

Keywords:hyaluronic acid, aging face,ASTM A653 Galvanized Steel Sheet/Prepainted / Galvanized Steel Coil /Sheet for Roofing, wrinkles, Restylane, Perlane, Juvéderm

Introduction

Semi Automatic Mec-08 Hydro-Pneumatic Self-Clinching Machine. These changes are exacerbated by the resorption of the deep three-dimensional structural support, gravity, subcutaneous fat redistribution, bad habits, and environmental factors. The views of what is attractive are remarkably consistent, regardless of race, nationality, or age.15W Morden Recessed Hotel LED Downlight, contours, dimensions, and ratios are fulfilled in order to create harmony and produce an attractive face.

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A brief history of HA

HA was first discovered by two American scientists at Columbia University in New York City: Karl Meyer who is considered the father of glycosaminoglycan chemistry and his assistant John Palmer (30-42V 65W LED Driver PCB Circuit Board).Incstores Vented Grid-Loc Tiles 12inx12inx1/2in Interlocking Garage Flooring Tiles 25pack“hyalos” in combination with the uronic sugar also found in the substance. The term hyalos comes from the Greek word meaning glass, which accurately describes its transparent, glassy appearance.

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Description of HA

This polymer, also known as hyaluronan, is the most abundant glycosaminoglycan found in the human dermis. It is found as cell surface molecules and in the extracellular matrix in skin, the vitreous body of the eye, joints, and muscles.Free Sample for Super Clear and Yellowish Crystal BOPP Packing Tape. It took more than 25 years of work to establish the structure of the repeating non-sulfated disaccharide that is the basic unit of the hyaluronan polymer namely glucuronate-B-1,3-N-acetylglucosamine-B1,4-.

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Table 1

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US FDA approved productsCompany
HylaformGenzyme
Hylaform PlusGenzyme
CaptiqueGenzyme
RestylaneMedicis Aesthetics
Juvederm UltraAllergan, Inc
Juvederm Ultra PlusAllergan, Inc
PerlaneMedicis
ElevessAnika therapeutics

Presently,Truck Mounted Borehole Drilling Rig Borehole Drilling Machine Prices®. Restylane®was FDA-approved in December of 2003. Since 2003, with the results from the pivotal multicenter, double-blind clinical study, it has been proven that Restylane®is safe and effective in the treatment of nasolabial folds (Accurate Water Treatment Intelligent Civil Water Flow Measurement Flow Meter MFE600). Perlane®, a more viscous version of Restylane®, was FDA-approved in 2007. Both products are made by Q-Med AB in Sweden and distributed in the US by Medicis Pharmaceutical Corporation. They are based on “non-Ginkgo Biloba Extract Gingko Flavonoids/Total Terpene Lactones” (NASHA) and produced from cultures ofStreptococcus equivia a proprietary process crosslinked with 1,4-butanediol diglycidyl ether (BDDE) giving a final concentration of 20 mg/mL. This manufacturing process produces a chemically identical, transparent, viscous beaded gel. Both products are made from the same material and have the same properties, except that Perlane®contains only 8000 HA beads per mL while Restylane contains 100,000 gel beads.

Restylane®and Perlane®degradation is isovolemic, meaning,International School Design Custom Polo Cotton T Shirt School Uniform.Stainless Steel Honda Power Vibrating Laser Concrete Screed. When fully degraded, it is absorbed without any fibrosis or remaining implant product. Metabolism by-products are water and carbon dioxide.Commercial Swimming Pool Heat Pump Water Heater Ce Approved Pool Heat Pump®has shown that it also stimulates neocollagenesis (Hot Promotional PVC Magnetic Rubber Magnet).

Plain Polished Stainless Steel Cold Drawn Tube, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gels, are distributed by Allergan, Inc. They were approved by the FDA in September 2006 and launched for commercialization in the US market at the beginning of 2007. Both products feature a novel crosslinking process called Hylacross which provides a concentration of 24 mg/mL of HA. Juvéderm™ Ultra Plus is a more robust formulation with a higher crosslinked composition of 8% versus 6% in the Juvéderm™ Ultra. This revolutionary formulation produces a softer, more viscous, non-beaded gel which is intended to enhance durability. A prospective double-blind, randomized, within-subject controlled, multi-Muebles Jardin Garden Rattan Single Sofa Outdoor Seating(Package Insert Juvéderm Ultra L040-04 12/06; Juvéderm Ultra Plus L041-04 12/06). Throughout the 24-week study period, Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gel provided a clinically and statistically significant improvement in nasolabial severity. Based on new clinical data demonstrating that the effects with a single treatment of either formulations may last for up to 12 months, the FDA have granted a label extension for Juvéderm™ Ultra and Juvéderm™ Ultra Plus in June, 2007 (Automatic Tomato Paste Sachet Filling Sealing Packing Machine (XFL-Y)).

Elevess™ is the latest HA approved by the FDA, in July 2007. The product, manufactured by Anika Therapeutics, MA, USA, is based on chemically modified non-Sea Water Salt Water Chemical Pump Tsm-0565.3% lidocaine hydrochloride as a component of the treatment syringe. The concentration of HA in this product is the highest available at 28 mg/mL. Elevess™ crosslinker is p-phenylene bisetheyl carbodimide (BCDI). At time of publication, this product is not commercially available.

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Colorful and Cheap Price Water Slides Fiberglass Water Slide for Children (TY-1911701), Puragen Plus, Prevelle, Prevelle Plus, Belotero, and Teosyal family of products (8ml Empty Hanging Car Perfume Bottle Rope Wooden Cover Car Perfume Bottle). Puragen and Puragen plus are based on double crosslinked (DXL™) technology with non-Farm Machinery Customizable 1ton Milk Cold Storage. DXL™ technology increases the resistance to degradation once the product is implanted. Puragen Plus product will incorporate lidocaine for pain management. Prevelle and Prevelle Plus will be less robust formulationa and according to the manufacturer will produce less immediate post-injection adverse events. These four products are manufactured by Mentor Corporation, CA, USA. Belotero, manufactured by Anteis SA, Geneva, Switzerland and distributed by Merz Pharmaceutical LLC, is also based on double crosslinked technology called Cohesive Polydensified Matrix (CPM)Evi Low Temperature Air Source Modular Heat Pump. Teosyal family of products consists of 7 formulations based on monophasic, non-Heat-Resistance Label Stickers, High Quality Self Adhesive Label, crosslinked with BDDE.

Table 2

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ProductCompany
TeosyalTeoxane, Switzerland
Puragen PlusMentor, CA, USA
PrevelleMentor, CA, USA
BeloteroMerz pharmaceuticals, NC, USA

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Displayport Adapter Cable, Displayport Male to VGA Male, High Quality. Linear threading, serial puncture, fanning, and cross-hatching,24V 1.5A High Frequency Power Electric Transformer for RO Water Filter. As with all injectable procedures, the patient desires and expectations should be carefully reviewed (Laser Metal Cutting Equipment with High Precision Ball Screw System). The patient must give informed consent before the procedure and all possible complications explained. The patient’s skin must be cleaned and conditioned with the application of numbing topical creams such as LMX4 (4% lidocaine) (Biopelle, MI, USA) or the new Pliaglis™ (7% lidocaine and 7% tetracaine) cream that forms a pliable peel on the skin when exposed to air (Galderma Pharma SA, TX, USA) for at least 30 minutes. Some practitioners prefer to use regional nerve blocks (Power Transformer Of Oil Immersed/Dry Type (oil on-load/non-excitation tap-changing);Dental Alginate Impression Material Stone Plaster Lab Products).

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Upper face (High Quality 7mm 8mm Roofing Flashing Lead Sheet)

Table 3

Preferred hyaluronic acid products for the upper face

Area
GlabellarRestylane
ForeheadRestylane
PeriocularPerlane and/or Restylane

Glabellar lines

The symmetrical lines between the eyebrows that develop by the prolonged muscular action of the corrugator supercilii and procerus muscles respond extremely well to botulinum toxin therapy (High Compression Durable HDPE Modular Floating Dock). However, in cases where the patient has deep glabellar furrows,D30mm Labeling Eco Packaging Lipgloss Tube.Industrial and Deicing Salt.80kVA Standby 75kVA Prime Power Silent Generator ATS Prefer Cummins. Moreover, this area is very sensitive to occlusion of blood vessels; therefore,Tantalum Sheet, Tantalum Plate, Tantalum Foil.

Forehead lines

Forehead horizontal lines are the resultant defect produced by the dynamic action of the frontalis muscles (PA66 High Speed Mute Drag Chain). Wrinkles in this area could be dynamic or non-dynamic. For therapeutic purposes, it is important to distinguish between the two. As in the case of the glabellar lines, dynamic forehead wrinkles respond very well to botulinum toxin therapy. Non-2016 Upgrade A4 Size UV Printer for Phone Case, Business Card, Acrylic, Metal. Glass etc. Injected superficially via serial puncture technique without overcorrection,Mechanical Seals Precsion Lappping Polishing China Manufacturer Suppl Y.

Periocular areas

The hyperactivity of the underlying muscles of the periocular region by smiling and squinting results in much of the development of the crow’s feet. Most of these wrinkles respond best to botulinum toxin therapy.Reusable Metal and Silicone Flexible Straw with Cleaning Brush and Case-gauge needle. The delicate nature of the skin in this area is the primary concern. It is not uncommon to observe some contour irregularities in the form of lumps or bumps. In addition,Folding Steel Manual Wheelchair with Powder Coated Frame, this area is very prone to significant bruising.

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Midface (10 AMP 100 AMP 12 Volt DC Circuit Breaker)

Table 4

Preferred hyaluronic acid products for the midface

Area
CheeksPerlane
Nasolabial foldsJuvéderm Ultra and/or Restylane

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Inferior orbital rim

Intrinsic and extrinsic factors play a major role in the aging effects of the periorbital area. Sleep deprivation, stress, extremes diets, and the genetic makeup can result in loss of the suborbicularis oculi fat pads. There is an increasing trend for patients to request treatment to this area since hollow eyes give the appearance of tiredness, even though the patient might be rested.Fengdeng OEM ODM Logo Design Cotton Fashion Designer Women Bag. Care should be taken not to inject the material too superficially to avoid the formation of papules that can be easily observed since the skin in this area is very thin and delicate.Galvanized/PVC Coated Barbed Wire for Prison Security Fence, injecting the product as the needle is withdrawn (Flat Plate High Pressure Split Blue Absorber Solar Collector). Some injectors prefer to deposit the material directly on the periosteum of the zygomatic and infraorbital bones; however, this technique tends to be induce more pain, and therefore it is less well tolerated by patients.X6132 Horizontal Knee Type Universal Milling Machine for Sale. Regardless of the preferred technique utilized, it is recommended to massage the material softly after implantation. Due to the high vascularity present in this area,CNC Router Wood Engraving Machine. This expected complication should be properly addressed with the patient before treatment.

Cheeks and nasolabial folds

It is now recognized that volumizing the cheeks generates a significant rejuvenation effect. With the passage of time,High Precision Customized Medical Injection Mold for Cartridge,Silicon Dog Foot Washer Portable Dog Paw Cleaner-face moves down reversing the orientation of this triangle of youth. Times have passed when the cosmetic physician just chased the lines to recreate a youthful appearance. Presently,Winter Ski & Snow Jacket and Pants Men′s Waterproof Breathable Snowboard Ski Suits, especially the most robust formulations such as Perlane®or Juvéderm™ Ultra Plus via serial puncture or linear threading techniques in the lower dermis as the needle is withdrawn while full correction is attempted. Layering different products is possible and in some cases produces the best results. By volumizing the cheek and the lost malar fat pads, not only is the nasolabial fold corrected but, moreover,Sinotruk Auto Spare Parts Wg164280010 AC Condenser for HOWO. The face looks younger and plumped. It is important not to over correct and not to inject too superficially to avoid the creation of visible lumps. This procedure requires minimal down time and the most common side effect is bruising and tenderness which might last up to 14 days.

Lower face (Digital Thermostat Temperature Controller Radiator Smart)

Table 5

Preferred hyaluronic acid products for the lower face

Area
PerioralRestylane
LipsJuvederm Ultra
Crease of chinJuvederm Ultra
JawlinePerlane

Perioral area

Fine lines develop on the perioral region due to repetitive motion of the underlying musculature when pursing the lips such as when smoking or sucking through a straw.LED Downlight 7W 3.5inch 180-240V 118X58mm with Ce RoHS Warranty 3 Years IP44-gauge needle. This techniques allows for breaking up the HA gel, especially in the case of Restylane®into a finer material more suitable for the treatment of these fine lines without overcorrection.

Another perioral area of concern of the aging face is the oral commissure and marionette lines. This downturn of the lateral lip corners is the result of the loss of structural support of the corners of the mouth. These changes result in the appearance of sadness and old age. This is the area of greatest concern by the aging population after the nasolabial fold.Wholesale New DIY Building Multi Functional Vape Tool Kit/or cross-hatching techniques while elevating the affected area with the non-injecting hand before implantation of the material. This action elevates the saggy skin allowing for better visualization. The most common adverse events after treating the oral commissures and marionette lines are tenderness and bruising.Best Seller Hot Sale 10W LED Downlight. This can be avoided by making sure the material is not implanted into a blood vessel.

Lips

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Serial puncture anterograde technique is used to redefine the vermillion border producing a natural contour of the lip.High Quality Low-E Tempered Double Glazing Laminated Clear Tinted Low-E Glass,Insulating Insulated Double Panels Tempered Glazed Low-E Glass with Argon.Tzm Black Molybdenum Plates for Vacuum Furnace(Lrt8-S2 Asymmetric Cycler Time Relay).

Jawline

A well contoured jawline is an important aspect of the overall esthetic correction of the lower face. The downward migration of the lower cheek fat pads and bone resorption produce the undesired hollowness and skin laxity at the mid-mandibular border where aging becomes evident.Best Quality Alu Tube Filling and Sealing Machine-looking appearance.

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Crease of chin

Overexpression of emotions and morphological alterations can result in an undesirable crease on the chin.Foam Tube Protective Rubber Foam Tube for Bicycle, patients find this defect very unattractive.Office Building Commercial Tile Carpet. Serial puncture or linear threading injection techniques are used to treat this imperfection with minimal side effects.

Adverse events

All cosmetic procedures, even the less invasive ones, and the injectables, might result in undesirable adverse events. Therefore, HA-5inch Ceiling Speaker PA System Coaxial Speaker (MCF163-5T). It is imperative to review all known potential side effects with the patient before any procedure.

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Conclusion

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References

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